Evidence map›Paper›PMID 39572219›Full record

ArticleThe European respiratory journal2024

Eosinophils, mucus plugs and clinical outcomes: findings from two COPD cohorts.

Alejandro A Diaz, Scott Grumley, Andrew Yen, Sushilkumar Sonavane, Rim Elalami, Maya Abdalla, Kangjin Kim, Pietro Nardelli, Sharon Brouha, Padma P Manapragada and 9 more

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Mucus Plugs and Eosinophilic Inflammation: Expanding the Paradigm to COPD.The journal of allergy and clinical immunology. In practice · 2026
    Review
  9. Article
  10. Article
  11. Adverse drug events associated with tiotropium: a real-world pharmacovigilance study of FDA adverse event reporting system database.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Alejandro A DiazHarvard Medical School, Boston, MA, USA adiaz6@bwh.harvard.edu.ORCID https://orcid.org/0000-0001-5037-2919
Scott GrumleyDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Andrew YenDepartment of Radiology, University of California San Diego, San Diego, CA, USA.
Sushilkumar SonavaneDepartment of Radiology, Mayo Clinic, Jacksonville, FL, USA.ORCID https://orcid.org/0000-0001-8823-7261
Rim ElalamiDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Maya AbdallaDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Kangjin KimChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Pietro NardelliHarvard Medical School, Boston, MA, USA.
Sharon BrouhaDepartment of Radiology, University of California San Diego, San Diego, CA, USA.
Padma P ManapragadaDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Mostafa AbozeedDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Muhammad Usman AzizDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Mohd ZahidDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Hrudaya P NathDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID https://orcid.org/0000-0003-0069-4068
Wei WangDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
James C RossHarvard Medical School, Boston, MA, USA.
Carrie L PistenmaaHarvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0003-1563-1916
Raul San José EstéparHarvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0002-3677-1996
Michael H ChoHarvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0002-4907-1657

Funding

Clinical Implications, Genomics, and Transcriptions of Mucus Plugging in SmokersR01HL149861 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., DIAZ, ALEJANDRO · 2020 to 2023
$3.2M
Understanding airway mucus dysfunction in population-based studiesR01HL164824 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DIAZ, ALEJANDRO · 2022 to 2025
$2.7M
Clinical implications and Proteomics of Bronchiectasis Progression in SmokersR01HL173017 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Alejandro Diaz, Raul San Jose Estepar · 2024 to 2026
$2.6M
The Pulmonary Vasculature and Platelets in Emphysema and COPDK23HL141651 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI PISTENMAA, CARRIE L · 2019 to 2023
$983k
NHLBI NIH HHS K23 HL141651NHLBI NIH HHS R01 HL149861NHLBI NIH HHS R01 HL164824NHLBI NIH HHS R01 HL173017
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39572219
PMCPMC13200003

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.