Evidence map›Paper›PMID 39570979›Full record

ArticlePLoS neglected tropical diseases2024

The cost of sleeping sickness vector control in Yasa Bonga, a health district in the Democratic Republic of the Congo.

Rian Snijders, Alexandra P M Shaw, Richard Selby, Inaki Tirados, Paul R Bessell, Alain Fukinsia, Erick Miaka, Fabrizio Tediosi, Epco Hasker, Marina Antillon

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rian SnijdersInstitute of Tropical Medicine Antwerp, Antwerp, Belgium.ORCID 0000-0002-2432-9818
Alexandra P M ShawUniversity of Edinburgh, Edinburgh, United Kingdom.
Richard SelbySightsavers, Haywards Heath, West Sussex, United Kingdom.
Inaki TiradosLiverpool School of Tropical Medicine, Liverpool, United Kingdom.
Paul R BessellIndependent consultant, Edinburgh, United Kingdom.
Alain FukinsiaProgramme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, Democratic Republic of the Congo.
Erick MiakaProgramme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, Democratic Republic of the Congo.
Fabrizio TediosiSwiss Tropical and Public Health Institute, Basel, Switzerland.
Epco HaskerInstitute of Tropical Medicine Antwerp, Antwerp, Belgium.
Marina AntillonSwiss Tropical and Public Health Institute, Basel, Switzerland.

Funding

Bill & Melinda Gates FoundationHuman African Trypanosomiasis Modelling and Economic Predictions for Policy (HAT MEPP) projectMargaret A. Cargill Foundation
6 · The paper itself

Abstract

Gambiense human African trypanosomiasis (gHAT), a neglected tropical disease caused by a parasite transmitted by tsetse flies, once inflicted over 30,000 annual cases and resulted in an estimated half a million deaths in the late twentieth century. An international gHAT control program has reduced cases to under 1,000 annually, encouraging the World Health Organization to target the elimination of gHAT transmission by 2030. This requires adopting innovative disease control approaches in foci where transmission persists. Since the last decade, case detection and treatment, the mainstay of controlling the disease, is supplemented by vector control using Tiny Targets, small insecticide-treated screens, which attract and kill tsetse. The advantages of Tiny Targets lie in their relatively low cost, easy deployment, and effectiveness. The Democratic Republic of Congo (DRC), bearing 65% of the 799 gHAT cases reported globally in 2022, introduced Tiny Targets in 2015. This study estimates the annual cost of vector control using Tiny Targets in the health district of Yasa Bonga in the DRC and identifies the main cost drivers. Economic and financial costs, collected from the provider's perspective, were used to estimate the average cost of tsetse control expressed as cost (i) per target used, (ii) per target deployed, (iii) per linear kilometre of river controlled, and (iv) per square kilometre protected by vector control. Sensitivity analyses were conducted on key parameters for results robustness. The estimated annual economic cost for protecting an area of 1,925 km2 was 120,000 USD. This translates to 5.30 USD per target used each year, 11 USD per target deployed in the field, 573 USD per linear km treated, and 62 USD per km2 protected. These costs in the DRC are comparable to those in other countries. The study provides valuable information for practitioners and policymakers making rational, evidence-based decisions to control gHAT.

Indexed as

Insect ControlInsect VectorsTrypanosomiasis, AfricanTsetse FliesAnimalsDemocratic Republic of the CongoHumansInsecticidesTrypanosoma brucei gambienseInsecticides

Identifiers

PMID39570979
PMCPMC11666030

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.