ArticlePloS one2024
Association between dietary niacin intake and chronic obstructive pulmonary disease among American middle-aged and older individuals: A cross-section study.
Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association between dietary niacin intake and mortality among US individuals with chronic obstructive pulmonary disease: data from the national health and nutrition examination survey 1999-2018.Frontiers in nutrition · 2025Article
- Association between asthma and cardiovascular disease: evidence from the national health and nutrition examination survey 1999-2018.Frontiers in cardiovascular medicine · 2024Article
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Authors and funding
6 authors.
Funding
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Abstract
backgroundThe attention towards the relationship between chronic obstructive pulmonary disease (COPD) and dietary intake is escalating. However, the effects of dietary niacin on COPD in middle and older individuals remains unclear. This study aimed to illuminate the connection between dietary niacin intake and COPD.
methodsThis cross-sectional study analyzed 7,170 participants from the National Health and Nutrition Examination Survey (NHANES) spanning the years 2013 to 2018. Participants were categorized into four groups based on quartiles of dietary niacin intake. To examine the association between covariates, dietary niacin intake, and COPD, we employed univariate analysis and multivariate logistic regression equations. Additionally, restricted cubic splines were utilized to assess linearity. Furthermore, we conducted stratified and interaction analyses to evaluate the stability of the relationship in diverse subgroups.
resultsAmong the 7,170 participants, 11.6% (834/7170) were diagnosed with COPD. The multivariable adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for COPD were 0.96 (95% CI: 0.77-1.19, p = 0.706), 0.78 (95% CI: 0.62-0.99, p = 0.038), and 0.76 (95% CI: 0.57-1.00, p = 0.047), respectively, when comparing the second, third, and fourth quartiles of niacin intake levels to the lowest quartile (p for trend = 0.017). An inverse association was observed between the occurrence of COPD and dietary niacin intake (nonlinear: p = 0.347). Stratified analyses revealed no significant differences or interactions.
conclusionOur findings suggest a potential link between increased dietary niacin intake and a decreased prevalence of COPD.
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