Trial reportJAMA network open2024
A Hearing Intervention and Health-Related Quality of Life in Older Adults: A Secondary Analysis of the ACHIEVE Randomized Clinical Trial.
Trial report in JAMA network open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03243422 (Aging and Cognitive Health Evaluation in Elders), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Aging and Cognitive Health Evaluation in Elders (ACHIEVE) Randomized Trial
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Hearing aids for mild to moderate hearing loss in adults.The Cochrane database of systematic reviews · 2026Pooled it
- Effects of Hearing Devices for Adults With Mild-to-Severe Hearing Loss: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of speech, language, and hearing research : JSLHR · 2026Pooled it
- Short-Term Audiometric Trajectories in Older Adults Receiving Systemic Human Umbilical Cord-Derived Mesenchymal Stem Cells: An Exploratory Single-Arm Substudy.Clinical interventions in aging · 2026Trial
- Music Enjoyment in Hearing Loss: Beyond Auditory Perception.Brain sciences · 2026Review
- Hearing Loss Among Older Adults: Epidemiology, Disparities, and Gaps in Research.Annual review of public health · 2026Review
- Mood and Cognitive Disorders Following Hearing Loss: Impact of Hearing Aid Timing.Audiology research · 2026Review
- Hearing Loss in Older Adults: Consistent Determinants Across Two Community-Based Cohorts in Southern China.Journal of aging research · 2026Article
- Association of sensory impairment severity and assistive device use with prevalent and incident motoric cognitive risk syndrome.BMC geriatrics · 2025Article
- Evaluating the Effectiveness of Community-Delivered Hearing Rehabilitation and Health Education Intervention on Social Isolation and Functioning Among Chinese Adults With Hearing Impairment: Protocol for Randomized Controlled Trial.JMIR research protocols · 2025Article
- Article
- Efficacy evaluation and clinical value exploration of secondary inpatient treatment for total deafness-type SSNHL: a single-center prospective study.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Funding
Abstract
Importance: Health-related quality of life is a critical health outcome and a clinically important patient-reported outcome in clinical trials. Hearing loss is associated with poorer health-related quality-of-life in older adults. Objective: To investigate the 3-year outcomes of hearing intervention vs health education control on health-related quality of life. Design, Setting, and Participants: This secondary analysis of a randomized clinical trial included participants treated for hearing loss at multiple US centers between 2018 and 2019 with 3-year follow-up completed in 2022. Eligible participants were aged 70 to 84 years, had untreated hearing loss, and were without substantial cognitive impairment. Participants were randomized (1:1) to hearing intervention or health education control and followed every 6 months. Intervention: Hearing intervention (provision of hearing aids and related technologies, counseling, education) or health education control (individual sessions covering topics relevant to chronic disease, disability prevention). Main Outcomes and Measures: Three-year change in the RAND-36 physical and mental health component scores over 3 years. The 8 individual domains of health-related quality-of-life were additionally assessed. Outcomes measured at baseline and at 6-month, 1-year, 2-year, and 3-year follow-ups. Intervention effect sizes estimated using a 2-level linear mixed effects model under the intention-to-treat principle. Results: A total of 977 participants were analyzed (mean [SD] age, 76.8 [4.0] years; 523 female [53.5%]; 112 Black [11.5%], 858 White [87.8%]; 521 had a Bachelor's degree or higher [53.4%]), with 490 in the hearing intervention and 487 in the control group. Over 3 years, hearing intervention (vs health education control) had no significant association with physical (intervention, -0.49 [95% CI, -3.05 to 2.08]; control, -0.92 [95% CI, -3.39 to 1.55]; difference, 0.43 [95% CI, -0.64 to 1.51]) or mental (intervention, 0.38 [95% CI, -1.58 to 2.34]; control, -0.09 [95% CI, -1.99 to 1.81]; difference, 0.47 [95% CI, -0.41 to 1.35]) health-related quality of life. Conclusions and Relevance: In this secondary analysis of a randomized clinical trial, hearing intervention had no association with physical and mental health-related quality-of-life over 3 years among older adults with hearing loss. Additional intervention strategies may be needed to modify health-related quality among older adults with hearing loss. Trial Registration: ClinicalTrials.gov Identifier: NCT03243422.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.