Evidence map›Paper›PMID 39570546›Full record

ArticleBreast cancer research and treatment2025

The functional TNF-α

Sherif Refaat, Hanan E Al-Rashidi, Rania A Abd El Azeem, Walaa E Nouh, Sahar Hamed, Zeinab R Attia

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In one paragraph

Article in Breast cancer research and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sherif RefaatDepartment of Medical Oncology, Oncology Center, Mansoura University, Mansoura, Egypt.ORCID http://orcid.org/0000-0002-9198-4900
Hanan E Al-RashidiMedical Laboratory Technology Department, College of Applied Medical Science, Taibah University, Madinah, Saudi Arabia.
Rania A Abd El AzeemMansoura University Children's Hospital, Mansoura University, Mansoura, Egypt.ORCID http://orcid.org/0000-0002-8578-6537
Walaa E NouhMansoura University Children's Hospital, Mansoura University, Mansoura, Egypt.ORCID http://orcid.org/0009-0006-2297-3956
Sahar HamedUrology and Nephrology Center, Mansoura University, Mansoura, Egypt. sahamed@mans.edu.eg.ORCID http://orcid.org/0000-0002-6847-6553
Zeinab R AttiaMansoura University Children's Hospital, Mansoura University, Mansoura, Egypt.ORCID http://orcid.org/0000-0003-1907-5419

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCompared with all other cancer types, Breast cancer (BC) among women has now exceeded them all as the primary reason for cancer worldwide. The BC represents 11.7% of all cancer cases and accounts for a predestined 2.3 million new cases. It is the fourth primary reason for cancer-associated deaths in women. With a staggering 200-400% increase in the relative incidence of BC in Egypt, there is an urgent need for new diagnostic or predictive markers. PURPOSE: The current investigation aims to explore the connection of the functional TNF-α

methodsThe ARMS-PCR method was used for genotyping TNF-α

resultsThe TNF-α

conclusionThis research is the first to correlate TNF-α

Indexed as

Breast NeoplasmsGenetic Predisposition to DiseasePolymorphism, Single NucleotideTumor Necrosis Factor-alphaAdultAgedAllelesBiomarkers, TumorCase-Control StudiesEgyptFemaleGene FrequencyGenetic Association StudiesGenotypeHumansMiddle AgedBiomarkers, TumorTumor Necrosis Factor-alphaBreast cancerCarcinogenesisPredictive indexRisk factorSingle-nucleotide polymorphismTNF-α

Identifiers

PMID39570546
PMCPMC11787156

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.