Trial reportApplied psychophysiology and biofeedback2025
Effect of Biofeedback Combined with Psychotherapy on Functional Constipation Complicated with Anxiety and Depression.
Trial report in Applied psychophysiology and biofeedback, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Advances in understanding intestinal microbiota mechanisms and intervention strategies for anxiety, depression, sleep disorders, and constipation.Frontiers in microbiology · 2026Review
- Research progress and controversies in the treatment of functional constipation-related depression with probiotics and prebiotics: a narrative review.Frontiers in pharmacology · 2026Review
- Deciphering the mechanistic involvement of PANoptosis in FC-MDD comorbidity through the gut-brain axis.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Biofeedback combined with psychotherapy has been recognized as a potential treatment for patients with functional constipation, anxiety and depression disorder. To validate the therapeutic effect of the biofeedback therapy, 120 patients with a clear diagnosis of functional constipation combined with anxiety and depression disorder were recruited, and then randomly divided into the control group (patients received gastrointestinal medication and anti-anxiety and depression medication) and the treatment group (patients received combined biofeedback and psychotherapy on the basis of the control group's treatment program). The treatment group was treated with biofeedback exercise twice a day for 7 days, supplemented with psychotherapy for a period of 2 months (half-month intervals for one time). Intestinal medications in the treatment group were stopped after one month of treatment. While for the control group, patients were maintained with gastrointestinal motivational drugs, probiotics, anti-anxiety and depression medications. Both groups reduced the dosage of anxiolytics and depressants after 3 months. The control and the treatment group were both effective and the latter had a more significant effect compared to the former. Moreover, the anxiety/depression symptom for patients in the treatment group was significantly milder than those in the control group. Notably, compared with pre-treatment symptoms, the treatment group showed a significant reduction in Pittsburgh sleep quality index (PSQI) scores in the sixth month (F = 0.008, P = 0.008). In summary, biofeedback combined with psychotherapy may improve relieve constipation patients' clinical symptoms, anxiety/depression state and sleep quality. The treatment is durable, safe, and easy to implement, so it is suitable for widely used.
Indexed as
Identifiers
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Registered trials
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