Evidence map›Paper›PMID 39570474›Full record

ArticleEJNMMI research2024

The value of radiomics based on 2-[18 F]FDG PET/CT in predicting WHO/ISUP grade of clear cell renal cell carcinoma.

Yun Han, Guanyun Wang, Jingfeng Zhang, Yue Pan, Jianbo Cui, Can Li, Yanmei Wang, Xiaodan Xu, Baixuan Xu

Abstract read
In one paragraph

Article in EJNMMI research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Role ofJapanese journal of radiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yun Han *Graduate School, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Guanyun Wang *Department of Nuclear Medicine, The First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Jingfeng ZhangGraduate School, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Yue PanDepartment of Nuclear Medicine, The First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Jianbo CuiGraduate School, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Can LiDepartment of Nuclear Medicine, The First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Yanmei WangGE Healthcare China, Pudong New Town, Shanghai, China.
Xiaodan XuDepartment of Nuclear Medicine, The First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Baixuan XuGraduate School, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, China. xbx301@163.com.ORCID http://orcid.org/0000-0002-6550-4758

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim is to develop and validate radiomics based on 2-[

methodsA total of 209 patients with 214 lesions, who underwent 2-[

resultsThe area under curve (AUC) of PET-0, PET-2.5%, PET-25%, PET-40% model in the training group were 0.881(95% CI: 0.822-0.940),0.883(95% CI: 0.825-0.942),0.889(95% CI: 0.831-0.946),0.887(95% CI: 0.826-0.948); and 0.878(95% CI: 0.777-0.978),0.876(95% CI: 0.776-0.977),0.871(95% CI: 0.769-0.972),0.882(95% CI: 0.786-0.979) in the testing group. Due to perfect prediction and verification performance, the volume of interest (VOI) from PET images with SUVmax threshold of 40% were selected to construct the radiomics model and combined model. The AUC of the clinical model and radiomics model was 0.859 (sensitivity = 0.846, specificity = 0.747) and 0.909 (sensitivity = 0.808, specificity = 0.751) in the training group, respectively; 0.882 (sensitivity = 0.857, specificity = 0.857) and 0.901 (sensitivity = 0.905, specificity = 0.833) in the testing group, respectively. In combined models, the AUC was 0.916, the sensitivity was 0.923 and the specificity was 0.808 in the training group; the AUC was 0.916, the sensitivity was 0.881 and the specificity was 0.792 in the training group.

conclusionRadiomics based on 2-[

Indexed as

Clear cell renal cell carcinomaPETRadiomicsWorld Health Organization/The International Society of Urological Pathology (WHO/ISUP) grade

Identifiers

PMID39570474
PMCPMC11582283

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.