SynthesisNeurosurgical review2024
Treatment strategies and outcomes for intracranial fusiform aneurysms: A systematic review and meta-analysis.
Synthesis in Neurosurgical review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Treatment of a giant terminal internal carotid artery aneurysm in a 10-year-old child by flow diversion: long-term outcome and lessons learned.BJR case reports · 2025Article
- Combined Endovascular and Microsurgical Treatment for a Giant Thrombosed Posterior Cerebral Artery Aneurysm: A Case Report.NMC case report journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFusiform aneurysms are a distinct subgroup of intracranial aneurysms with unique characteristics and pose a treatment challenge compared to common saccular aneurysms. Traditionally, surgery was the main treatment; however, endovascular techniques are gaining favor.
methodsWe searched major databases for studies on treatment, clinical outcomes, and radiological outcomes of intracranial fusiform aneurysms published before May 31st, 2023 in order to compare surgical Vs endovascular treatment strategies. Pooled data analysis was performed using a random-effects model.
resultsThis systematic review and meta-analysis analyzed 1704 patients with 1737 fusiform aneurysms from 63 studies. Endovascular treatment, particularly stent-assisted coiling and stenting, emerged as the preferred approach with lower mortality and complication rates compared to surgery. Aneurysm location played a role in outcomes, with anterior circulation aneurysms generally faring better. Deconstructive strategies, designed to occlude the parent artery, carried a doubled risk of complications compared to reconstructive approaches, which aim to preserve blood flow (OR: 2.188; 95% CI: 1.474-3.248; p < 0.001).
conclusionEndovascular techniques are becoming the mainstay of treatment for fusiform aneurysms, offering improved safety and efficacy compared to surgery. Anterior circulation location and reconstructive strategies are associated with better outcomes. However, no significant differences in OR for early complete occlusion were found between surgery and endovascular techniques at discharge and follow-up with very low heterogeneity among studies.
Indexed as
Identifiers
39570441What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.