Evidence map›Paper›PMID 39570398›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2025

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Chunxia Qin, Xiangming Song, Shiran Sun, Yangmeihui Song, Weiwei Ruan, Yongkang Gai, Ming Yang, Chidan Wan, Xiaoli Lan

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05006326 (A Prospective Study of Clinical Application of 68Ga-PSMA PET/MR for Diagnosis and Staging in Hepatocellular Carcinoma), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05006326 naunknown statusnot on this map

A Prospective Study of Clinical Application of 68Ga-PSMA PET/MR for Diagnosis and Staging in Hepatocellular Carcinoma

TypeinterventionalSponsorUnion Hospital, Tongji Medical College, Huazhong University of Science and TechnologyRan2021 to 2023Enrolled30ConditionsMalignant NeoplasmArms68Ga-PSMA, PET/MR, PET/CT
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Diagnostic Performance of PSMA PET/MRI in Characterizing LI-RADS 3 Observations in Patients with Cirrhosis.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  2. Article
  3. Non-invasive diagnosis of liver fibrosis via MRI using targeted gadolinium-based nanoparticles.European journal of nuclear medicine and molecular imaging · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chunxia Qin *Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China.
Xiangming Song *Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China.
Shiran Sun *Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China.
Yangmeihui SongDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China.
Weiwei RuanDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China.
Yongkang GaiDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China.
Ming YangDepartment of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China.
Chidan WanDepartment of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China. wanchidan@hust.edu.cn.
Xiaoli LanDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China. xiaoli_lan@hust.edu.cn.ORCID 0000-0002-7263-7399

Funding

Hubei Province Science and Technology Innovation Team [2022] No. 72Key Project of Hubei Province Natural Science Foundation No. 2021CFA008National Natural Science Foundation of China 82030052National Natural Science Foundation of China 82171985
6 · The paper itself

Abstract

purposeRadiolabeled probes targeting prostate-specific membrane antigen (PSMA) have been used in prostate cancer. Moreover, PSMA is also overexpressed on neovessels in hepatocellular carcinoma (HCC). This study aimed to preliminarily evaluate the diagnostic effectiveness of [

methodsPatients suspected of HCC were prospectively enrolled in this single-center study (NCT05006326, 2021-08-16) to perform [

resultsA total of 12 patients (ten men and two women; mean age 58.75 ± 12.08 years) were included. Ten patients were diagnosed with HCC, 2 with intrahepatic cholangiocarcinoma (ICC), and 4 with hemangioma. The SUVmax, TLR, TBR, and TPR of HCC primary tumors were higher than those of ICC and hemangioma. The diagnostic accuracy of [

conclusionUtilizing a hybrid PET/MRI system to combine [

trial registrationNCT05006326. Registered August 16, 2021, https://clinicaltrials.gov/study/NCT05006326 .

Indexed as

Carcinoma, HepatocellularDipeptidesHeterocyclic Compounds, 1-RingLiver NeoplasmsMagnetic Resonance ImagingPositron-Emission TomographyAdultAgedFemaleGallium IsotopesGallium RadioisotopesHumansMaleMiddle AgedMultimodal ImagingProstate-Specific AntigenDipeptidesGallium IsotopesGallium RadioisotopesHeterocyclic Compounds, 1-RingProstate-Specific AntigenPSMA-617[68Ga]Ga-PSMA-617Diagnostic testHepatocellular carcinomaPET/MRIProstate-specific membrane antigen

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.