Evidence map›Paper›PMID 39570195›Full record

ArticleCurrent protocols2024

Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements.

Stefanie Rauch, Francesco Costacurta, Dorothee von Laer, Emmanuel Heilmann

Abstract read
In one paragraph

Article in Current protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefanie RauchInstitute of Virology, Medical University of Innsbruck, Innsbruck, Austria.ORCID https://orcid.org/0009-0007-7415-0211
Francesco CostacurtaInstitute of Virology, Medical University of Innsbruck, Innsbruck, Austria.
Dorothee von LaerInstitute of Virology, Medical University of Innsbruck, Innsbruck, Austria.
Emmanuel HeilmannInstitute of Virology, Medical University of Innsbruck, Innsbruck, Austria.ORCID https://orcid.org/0000-0001-8148-9490

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protease inhibitors are among the most powerful antiviral drugs. They have been used successfully against viruses, such as the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Protease inhibitor screening tools are therefore important to identify inhibitors that have the potential to become antiviral drugs. In this article, we describe newly developed cell- and virus replicon-based platforms to screen inhibitors. We developed the methods presented here by genetically modifying vesicular stomatitis virus, a model virus from the family Rhabdoviridae. © 2024 The Author(s). Current Protocols published by Wiley Periodicals LLC. Basic Protocol: M

Indexed as

Protease InhibitorsAntiviral AgentsHumansPeptide HydrolasesSARS-CoV-2TransfectionVesicular stomatitis Indiana virusVesiculovirusAntiviral AgentsPeptide HydrolasesProtease InhibitorscoronavirusesMproprotease inhibitorsSARS‐CoV‐2vesicular stomatitis virus (VSV)

Identifiers

PMID39570195
PMCPMC11580764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.