ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2025
Development and validation of the D-PACE scoring system to predict delayed high-grade conduction disturbances after transcatheter aortic valve implantation.
Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Extremely Late Complete AV Block After TAVR: ECG Clues and Correction With Left Bundle Branch Pacing.Pacing and clinical electrophysiology : PACE · 2026Article
- Optimized Balloon-Expandable Transcatheter Aortic Valve Implantation and Clinical Outcomes.JACC. Advances · 2026Article
- Impact of early PR interval prolongation after transcatheter aortic valve Implantation (TAVI) on the onset of high-grade conduction disturbances.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Conduction Disorders: The Achilles' Heel of TAVR?Journal of clinical medicine · 2026Review
- A Streamline Strategy for Indication and Length of Telemetry Monitoring After TAVR.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Observational
- Geriatric nutritional risk index improves risk scoring for mortality after TAVR compared to established scores.Frontiers in cardiovascular medicine · 2026Article
- Aortic Valve Replacement vs. Balloon-Expandable and Self-Expandable Transcatheter Implantation in Low-Risk Patients.Journal of clinical medicine · 2025Article
- Prospective Observational Study on the Accuracy of Predictors of Permanent Pacemaker Secondary to High-Grade Atrioventricular Conduction Block After TAVI (CONDUCT-TAVI).Circulation. Cardiovascular interventions · 2025Observational
- Managing Bradycardia in Patients After Transcatheter Tricuspid Valve Replacement.Structural heart : the journal of the Heart Team · 2025Review
- The challenge of early discharge after transcatheter aortic valve implantation.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025Article
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22 authors.
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Abstract
backgroundNew conduction disturbances are frequent after transcatheter aortic valve implantation (TAVI). Refining our ability to predict high-grade atrioventricular block (AVB) occurring later than 24 hours after the procedure would be useful in order to select patients eligible for early discharge.
aimsThis study was designed to identify predictors of high-grade AVB occurring between 24 hours and 30 days after TAVI and to develop and validate a predictive risk score.
methodsWe analysed clinical, procedural, and electrocardiographic parameters of 1,290 TAVI patients. Independent predictors of delayed high-grade AVB were used to develop the predictive score, which was then externally validated in a cohort of 936 patients.
resultsImplantation of self-expanding valves, greater implantation depth, longer PR interval in preprocedural electrocardiogram (ECG) and greater increase of PR duration in next-day ECG, preprocedural right bundle branch block (RBBB) and new-onset left bundle branch block or RBBB that persisted in next-day ECG were independent predictors of delayed high-grade AVB and were combined to develop the Delayed atrioventricular block Prediction for eArly disChargE (D-PACE) score. The areas under the curve of the score were 0.879 (95% confidence interval [CI]: 0.835-0.923) and 0.799 (95% CI: 0.730-0.868) in the derivation and validation cohorts, respectively. Based on the score, patients can be classified into three risk categories; low-risk patients demonstrated an incidence of delayed AVB of less than 1% and are ideal candidates for next-day discharge.
conclusionsThe D-PACE score can be used to stratify TAVI patients according to their risk of delayed high-grade AVB and thereby identify those suitable for next-day discharge.
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