Evidence map›Paper›PMID 39569703›Full record

ArticleClinical implant dentistry and related research2025

The Effect of NiTi Brush, Polishing Brush, and Chemical Agent on the Dental Implant Surface Morphology and Cytocompatibility.

Giulia Brunello, Kathrin Becker, Nicole Rauch, Frank Schwarz, Jürgen Becker

Abstract read
In one paragraph

Article in Clinical implant dentistry and related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giulia BrunelloDepartment of Oral Surgery, University Hospital of Düsseldorf, Düsseldorf, Germany.ORCID https://orcid.org/0000-0003-1436-0085
Kathrin BeckerDepartment of Orthodontics and Dentofacial Orthopedics, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Nicole RauchDepartment of Oral Surgery, University Hospital of Düsseldorf, Düsseldorf, Germany.
Frank SchwarzDepartment of Oral Surgery and Implantology, Goethe University, Frankfurt, Germany.ORCID https://orcid.org/0000-0002-5873-9903
Jürgen BeckerDepartment of Oral Surgery, University Hospital of Düsseldorf, Düsseldorf, Germany.

Funding

CAMLOG Biotechnologies AG (Basel, Switzerland)Oral Reconstruction Foundation Ref.OFR12101
6 · The paper itself

Abstract

objectivesTo in vitro investigate the effect of different implant surface decontamination methods and treatment storing conditions on implant surface morphology and cell viability. MATERIALS AND

methodsTitanium disks with a sand-blasted and acid-etched surface (Promote, PRO) were treated with diamond polishing brushes (BRUSH), nickel-titanium brushes (NITI), or phenol and sulfuric acid-gel (GEL). The disks were stored in saline (-S) or left exposed to air overnight (-A). Untreated (PRO) and machined (MACHINED) disks were used as controls. GEL samples were treated for the 60 s, while the operative time was recorded for BRUSH and NITI. The samples were subjected to scanning electron microscopy (SEM), surface roughness measurements, and cell viability (SaOS-2 cells, 7 days) assessment.

resultsThe operative time was shorter for NITI than for BRUSH (p = 0.017). The original surface morphology (PRO) was not altered in the GEL group, in contrast with what was observed for BRUSH and NITI. The type of storage did not influence the surface morphology. No significant differences in Sa and Sz were observed among the groups, except for MACHINED, which presented lower Sa values (p < 0.05). Cells were able to proliferate on all surfaces. NITI-S showed significantly higher cell viability compared to all groups (p ≤ 0.001), except for NITI-A and MACHINED. Among the treated groups, only one additional significant difference was found, as NITI-A performed better than GEL-S.

conclusionsNone of the investigated protocols compromised the cytocompatibility of the titanium dental implant surface. The best results were registered in the NITI group when the samples were stored in saline. Future studies should confirm the effectiveness of the proposed methods in removing bacterial biofilm from contaminated implant surfaces.

Indexed as

Dental ImplantsDental PolishingNickelTitaniumAcid Etching, DentalCell SurvivalDecontaminationHumansMaterials TestingMicroscopy, Electron, ScanningPhenolSulfuric AcidsSurface PropertiesDental ImplantsNickelPhenolsulfuric acidSulfuric AcidsTitaniumtitanium nickelidehydrophilicityimplantoplastyimplant surface modificationperi‐implantitis

Identifiers

PMID39569703
PMCPMC11798888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.