Evidence map›Paper›PMID 39569684›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Robotic Laser Tissue Soldering for Atraumatic Soft Tissue Fusion Guided by Fluorescent Nanothermometry.

Oscar Cipolato, Tobias Leuthold, Marius Zäch, Georg Männel, Sam Aegerter, Calinda Sciascia, Alexander Jessernig, Marco von Salis, Sima Sarcevic, Jachym Rosendorf and 4 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Oscar CipolatoNanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092, Switzerland.ORCID https://orcid.org/0000-0003-2268-0927
Tobias LeutholdNanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092, Switzerland.
Marius ZächNanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092, Switzerland.
Georg MännelFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Mönkhoferweg, 23562, Lübeck, Germany.ORCID https://orcid.org/0000-0003-3508-9052
Sam AegerterNanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092, Switzerland.
Calinda SciasciaNanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092, Switzerland.
Alexander JessernigNanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092, Switzerland.
Marco von SalisNanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092, Switzerland.
Sima SarcevicDepartment of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 923/80, Pilsen, 32300, Czech Republic.
Jachym RosendorfDepartment of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 923/80, Pilsen, 32300, Czech Republic.
Vaclav LiskaDepartment of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 923/80, Pilsen, 32300, Czech Republic.
Dennis KundratFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Mönkhoferweg, 23562, Lübeck, Germany.
Romain QuidantNanophotonic Systems Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092, Switzerland.
Inge K HerrmannNanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092, Switzerland.ORCID https://orcid.org/0000-0002-3018-6796

Funding

European Union - European Regional Development Fund (ERDF), the Federal Government and Land Schleswig Holstein 12420002Oertli FoundationSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 181290
6 · The paper itself

Abstract

Minimally invasive surgical techniques, including endoscopic and robotic procedures, continue to revolutionize patient care, for their ability to minimize surgical trauma, thus promoting faster recovery and reduced hospital stays. Yet, the suturing of soft tissues ensuring damage-free tissue bonding during these procedures remains challenging due to missing haptics and the fulcrum effect. Laser tissue soldering has potential in overcoming these issues, offering atraumatic seamless tissue fusion. To ensure the precision and safety of laser tissue soldering, the study introduces feedback-controlled fluorescent nanothermometry-guided laser tissue soldering using nanoparticle-protein solders within endoscopic and robotic contexts. Temperature-sensitive fluorescent nanoparticles embedded in the solder provide surgeons with immediate feedback on tissue temperatures during laser application, all while within the confines of minimally invasive (robotic) surgical setups. By integrating fluorescent nanothermometry-guided laser tissue surgery into endoscopic and robotic surgery, the study paves the way for a new approach for safe and atraumatic soft tissue joining, especially in regions where traditional suturing is unfeasible.

Indexed as

Minimally Invasive Surgical ProceduresRobotic Surgical ProceduresThermometryAnimalsHumansLasersNanoparticlesfeedback controllaparoscopyminimally invasive surgerynanomaterialssuturing

Identifiers

PMID39569684
PMCPMC11831491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.