ArticleAutism research : official journal of the International Society for Autism Research2025
Elevated parkinsonism symptoms in autism during middle and older adulthood are linked with psychosocial, physical health, and mental health outcomes.
Article in Autism research : official journal of the International Society for Autism Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Autism and Neurodegeneration: Distinct Disorders or a Shared Biological Continuum?Brain sciences · 2026Review
- Disruption of DNA Repair as an Emerging Epigenetic Mechanism Underlying Autism Spectrum Disorder.Current psychiatry reports · 2026Review
- Atypical Visually Guided Precision Grip Control in Middle-Aged and Older Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026Article
- Antipsychotic Drug Prescriptions for Transition-Age Youth on the Autism Spectrum.Journal of autism and developmental disorders · 2026Article
- Subcortical brain volume variations in autistic individuals across the lifespan.Molecular autism · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Evidence is growing for a link between parkinsonism, or the motor symptoms associated with Parkinson's Disease and autism. However, research to date has yet to examine whether the presence of these motoric symptoms impacts critical adult outcomes in autism. Therefore, the current study utilized a screening measure to bifurcate a relatively large (n = 379) sample of middle and older age autistic adults (40-83 years) into parkinsonism screen positive (n = 119) versus parkinsonism screen negative (n = 260) groups in order to compare them on broad metrics of daily living skills and subjective quality of life as well as non-motoric features linked to parkinsonism, namely memory problems, sleep quality, and depression symptoms. Overall, co-occurring parkinsonism was linked with lower subjective quality of life, more memory problems, lower sleep quality, and greater depression symptoms in autistic adults. Taken together, these findings implicate an important co-occurring motoric phenotype in middle and older adulthood for autistic people that could have significant real-world impacts yet has been largely neglected in the extant literature to date.
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Registered trials
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