Evidence map›Paper›PMID 39569543›Full record

ArticleInternational journal of stroke : official journal of the International Stroke Society2025

International practice patterns and perspectives on endovascular therapy for the treatment of cerebral venous thrombosis.

Benjamin A Brakel, Alexander D Rebchuk, Johanna Ospel, Yimin Chen, Manraj Ks Heran, Mayank Goyal, Michael D Hill, Zhongrong Miao, Xiaochuan Huo, Simona Sacco and 25 more

Abstract read
In one paragraph

Article in International journal of stroke : official journal of the International Stroke Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Cerebral venous thrombosis: Current management, recent advances and future directions.International journal of stroke : official journal of the International Stroke Society · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Benjamin A BrakelFaculty of Medicine, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0003-1388-3490
Alexander D RebchukDivision of Neurosurgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.
Johanna OspelDepartment of Radiology, University of Calgary, Calgary, AB, Canada.
Yimin ChenDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Manraj Ks HeranDepartment of Radiology, University of British Columbia, Vancouver, BC, Canada.
Mayank GoyalDepartment of Radiology, University of Calgary, Calgary, AB, Canada.
Michael D HillDepartment of Radiology, University of Calgary, Calgary, AB, Canada.ORCID 0000-0002-6269-1543
Zhongrong MiaoInterventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-9642-9415
Xiaochuan HuoNeurological Disease Center, Beijing Anzhen Hospital, Beijing, China.
Simona SaccoNeuroscience Section, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Shadi YaghiDepartment of Neurology, Brown University, Providence, RI, USA.ORCID 0000-0003-0031-1004
Ton Duy MaiStroke Centre, Bach Mai Hospital, Ha Noi Medical University, Hanoi, Vietnam.ORCID 0000-0002-7210-3522
Götz ThomallaDepartment of Neurology, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Grégoire BoulouisDepartments of Diagnostic and Interventional Neuroradiology, University of Tours, Tours, France.
Hiroshi YamagamiDepartment of Stroke Neurology, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Wei HuDepartment of Neurology, The First Affiliated Hospital of University of Science and Technology of China, Hefei, China.
Simon NagelDepartment of Neurology, Klinikum Ludwigshafen, Ludwigshafen, Germany.
Volker PuetzDepartment of Neurology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Espen Saxhaug KristoffersenDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0002-8999-5424
Jelle DemeestereDepartment of Neurology, Leuven University Hospital, Leuven, Belgium.ORCID 0000-0001-8186-0237
Zhongming QiuDepartment of Neurology, The 903rd Hospital of The Chinese People's Liberation Army, Hangzhou, China.ORCID 0000-0002-1622-9526
Mohamad AbdalkaderDepartment of Neurology, Radiology, Boston University School of Medicine, Boston, MA, USA.
Sami Al KasabDepartment of Neurology, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0001-8909-9761
James E SieglerDepartment of Neurology, University of Chicago, Chicago, IL, USA.
Daniel StrbianDepartment of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Urs FischerDepartment of Neurology, University Hospital Bern, University of Bern, Bern, Switzerland.ORCID 0000-0003-0521-4051
Jonathan CoutinhoDepartment of Neurology, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands.
Anita MunckhofDepartment of Neurology, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands.ORCID 0000-0001-6028-3426
Diana Aguiar de SousaStroke center, Lisbon Central University Hospital-ULS S José, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.ORCID 0000-0002-6702-7924
Bruce Cv CampbellDepartment of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0003-3632-9433
Jean RaymondDepartment of Radiology, Service of Interventional Neuroradiology, Université de Montréal, Montreal, QC, Canada.
Xunming JiDepartment of Neurosurgery, Xuanwu Hospital, Beijing, China.ORCID 0000-0003-0293-2744
Gustavo SaposnikStroke Outcomes Research & Decision Neuroscience Unit, Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-5950-9886
Thanh N NguyenDepartment of Neurology, Radiology, Boston University School of Medicine, Boston, MA, USA.ORCID 0000-0002-2810-1685
Thalia S FieldDivision of Neurology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-1176-0633

Funding

Kinetic analysis of acute stroke secondary prevention trials: Insights from combined datasets guiding future trial designR61NS135583 · NINDS · UNIVERSITY OF CHICAGO · PI BRORSON, JAMES R. · 2024 to 2025
$762k
NINDS NIH HHS R61 NS135583
6 · The paper itself

Abstract

backgroundCerebral venous thrombosis (CVT) accounts for 0.5-1% of all strokes. The role of endovascular therapy (EVT) in the management of CVT remains controversial and variations in practice patterns are not well known.

aimsHere, we present a comprehensive, international characterization of practice patterns and perspectives on the use of EVT for CVT.

methodsA comprehensive 42-question survey was distributed to stroke clinicians globally from May to October 2023, asking about practice patterns and perspectives on the use of EVT for CVT.

resultsThe overall response rate was 31% (863 respondents of 2744 invited) across 61 countries. The majority of respondents (74%) supported the use of EVT for CVT in certain clinical situations. Key considerations for decision-making in using EVT favored clinical over radiographic/procedural factors and included worsening level of consciousness (86%) and worsening neurological deficits (76%). In the past 3 years, 56% of respondents used EVT for the treatment of CVT, with most (49.5%) involved in two to five cases. Among interventionalists, significant variability existed in the techniques used for EVT (

conclusionOur survey reveals significant heterogeneity in approaches to EVT for CVT, and provides a comprehensive characterization of indications, techniques, and long-term management used by clinicians internationally. This resource will aid in optimizing patient selection and endovascular treatments for future trials.

Indexed as

Endovascular ProceduresIntracranial ThrombosisPractice Patterns, Physicians'Venous ThrombosisHumansSurveys and QuestionnairesThrombectomyanticoagulantsendovascular proceduresStrokethrombectomyvenous thrombosis

Identifiers

PMID39569543
PMCPMC11874609

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.