Evidence map›Paper›PMID 39569402›Full record

ReviewInternational journal of extreme manufacturing2025

Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration.

I Deniz Derman, Taino Rivera, Laura Garriga Cerda, Yogendra Pratap Singh, Shweta Saini, Hasan Erbil Abaci, Ibrahim T Ozbolat

Abstract readReview
In one paragraph

Review in International journal of extreme manufacturing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  14. Bioprinted skin: from lab bench to clinic, what matters now and what's next.Frontiers in bioengineering and biotechnology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

I Deniz DermanEngineering Science and Mechanics Department, Penn State University, University Park, PA, United States of America.ORCID https://orcid.org/0000-0001-9824-9071
Taino RiveraBiomedical Engineering Department, Penn State University, University Park, PA, United States of America.ORCID https://orcid.org/0009-0009-8650-5264
Laura Garriga CerdaDepartment of Dermatology, Columbia University Irving Medical Center, New York, NY, United States of America.ORCID https://orcid.org/0009-0002-4895-0497
Yogendra Pratap SinghEngineering Science and Mechanics Department, Penn State University, University Park, PA, United States of America.ORCID https://orcid.org/0000-0003-4941-9323
Shweta SainiThe Huck Institutes of the Life Sciences, Penn State University, University Park, PA, United States of America.
Hasan Erbil AbaciDepartment of Dermatology, Columbia University Irving Medical Center, New York, NY, United States of America.ORCID https://orcid.org/0000-0002-4735-7790
Ibrahim T OzbolatEngineering Science and Mechanics Department, Penn State University, University Park, PA, United States of America.ORCID https://orcid.org/0000-0001-8328-4528

Funding

Intraoperative bioprinting of composite tissues with zonal stratification for craniomaxillofacial reconstructionR01DE028614 · NIDCR · PENNSYLVANIA STATE UNIVERSITY, THE · PI OZBOLAT, IBRAHIM · 2020 to 2024
$2.8M
Investigating the role of Lef1 in fibroblast lineages to induce skin regeneration and reverse agingR01AR078743 · NIAMS · WASHINGTON STATE UNIVERSITY · PI DRISKELL, RYAN · 2021 to 2025
$1.6M
Developing in situ transcriptomics of a bioprinted follicular skin modelR21AR082668 · NIAMS · JACKSON LABORATORY · PI OH, JULIA, OZBOLAT, IBRAHIM · 2023 to 2023
$439k
NIAMS NIH HHS R01 AR078743NIAMS NIH HHS R21 AR082668NIDCR NIH HHS R01 DE028614
6 · The paper itself

Abstract

This comprehensive review explores the multifaceted landscape of skin bioprinting, revolutionizing dermatological research. The applications of skin bioprinting utilizing techniques like extrusion-, droplet-, laser- and light-based methods, with specialized bioinks for skin biofabrication have been critically reviewed along with the intricate aspects of bioprinting hair follicles, sweat glands, and achieving skin pigmentation. Challenges remain with the need for vascularization, safety concerns, and the integration of automated processes for effective clinical translation. The review further investigates the incorporation of biosensor technologies, emphasizing their role in monitoring and enhancing the wound healing process. While highlighting the remarkable progress in the field, critical limitations and concerns are critically examined to provide a balanced perspective. This synthesis aims to guide scientists, engineers, and healthcare providers, fostering a deeper understanding of the current state, challenges, and future directions in skin bioprinting for transformative applications in tissue engineering and regenerative medicine.

Indexed as

3D bioprintingbiofabricationbiosensorsskin modelsskin tissue engineering

Identifiers

PMID39569402
PMCPMC11574952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.