Evidence map›Paper›PMID 39569379›Full record

ArticleiScience2024

Distinct brain and lung endothelial miRNA/mRNA profiles after exposure to

Nahla Galal Metwally, Maria Del Pilar Martinez Tauler, Hanifeh Torabi, Johannes Allweier, Sara Mohamed, Maryeva Bessemoulin, Philip Bouws, Fatima Alshikh, Yifan Wu, Milad Temori and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Nahla Galal MetwallyResearch Group Host-Parasite Interaction, Hamburg, Germany.
Maria Del Pilar Martinez TaulerResearch Group Host-Parasite Interaction, Hamburg, Germany.
Hanifeh TorabiResearch Group Host-Parasite Interaction, Hamburg, Germany.
Johannes AllweierResearch Group Host-Parasite Interaction, Hamburg, Germany.
Sara MohamedResearch Group Host-Parasite Interaction, Hamburg, Germany.
Maryeva BessemoulinResearch Group Host-Parasite Interaction, Hamburg, Germany.
Philip BouwsResearch Group Host-Parasite Interaction, Hamburg, Germany.
Fatima AlshikhResearch Group Host-Parasite Interaction, Hamburg, Germany.
Yifan WuResearch Group Host-Parasite Interaction, Hamburg, Germany.
Milad TemoriResearch Group Host-Parasite Interaction, Hamburg, Germany.
Tabea SchellResearch Group Host-Parasite Interaction, Hamburg, Germany.
Maximillian RakotonirinalalaoResearch Group Host-Parasite Interaction, Hamburg, Germany.
Barbara HoneckerResearch Group Host-Parasite Interaction, Hamburg, Germany.
Katharina HöhnCellular Parasitology Department, Hamburg, Germany.
Thomas JacobsResearch Group Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Holger HeineDivision of Innate Immunity, Research Center Borstel, Leibniz Lung Center (Airway Research Center North (ARCN), German Centre for Lung Research (DZL), Borstel, Germany.
Iris BruchhausResearch Group Host-Parasite Interaction, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) control 60% of genes expressed in the human body, but their role in malaria pathogenesis is incompletely understood. Here, we demonstrate cell type-specific alterations to the miRNA profiles during the early response to malaria infection in brain and lung endothelial cells (ECs). In brain ECs, incubation with

Indexed as

Biological sciencesDiseaseMicrobiology parasiteNeuroscience

Identifiers

PMID39569379
PMCPMC11576406

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.