Evidence map›Paper›PMID 39569366›Full record

ArticleiScience2024

SART1 modulates poly-(ADP-ribose) chain accumulation and PARP1 chromatin localization.

Samuele Lodovichi, Thales C Nepomuceno, Nicholas T Woods, Uwe Rix, John M Koomen, Achille Pellicioli, Alvaro Galli, Alvaro N A Monteiro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samuele LodovichiDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Thales C NepomucenoDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Nicholas T WoodsGastrointestinal Cancer Program, Eppley Institute for Research in Cancer, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Uwe RixDepartment of Drug Discovery, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
John M KoomenMolecular Oncology and Molecular Medicine Program, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
Achille PellicioliDipartimento di Bioscienze, Università degli Studi di Milano, 20131 Milano, Italy.
Alvaro GalliYeast Genetics and Genomics, Laboratory of Functional Genetics and Genomics, Institute of Clinical Physiology, CNR, 56125 Pisa, Italy.
Alvaro N A MonteiroDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
RESISTANCE AND RESPONSE SIGNALING TO PARP1 INHIBITORS IN OVARIAN CANCERR21CA252373 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI MONTEIRO, ALVARO N, RIX, UWE · 2021 to 2022
$420k
NCI NIH HHS P30 CA076292NCI NIH HHS R21 CA252373
6 · The paper itself

Abstract

PARP1 inhibitors (PARPis) are used for treatment of cancers with mutations in

Indexed as

Cell biologyMolecular biologyOmics

Identifiers

PMID39569366
PMCPMC11576398

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.