Evidence map›Paper›PMID 39569331›Full record

ArticleNanoscale advances2024

Amphoteric β-cyclodextrin coated iron oxide magnetic nanoparticles: new insights into synthesis and application in MRI.

Federica Calsolaro, Francesca Garello, Eleonora Cavallari, Giuliana Magnacca, Mikhail V Trukhan, Maria Carmen Valsania, Giancarlo Cravotto, Enzo Terreno, Katia Martina

Abstract read
In one paragraph

Article in Nanoscale advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Federica CalsolaroDepartment of Drug Science and Technology, University of Turin Via P. Giuria 9 10125 Turin Italy katia.martina@unito.it.ORCID https://orcid.org/0000-0001-8059-1071
Francesca GarelloDepartment of Molecular Biotechnology and Health Sciences, University of Turin Piazza Nizza 44/bis 10126 Turin Italy enzo.terreno@unito.it.ORCID https://orcid.org/0000-0002-7150-2003
Eleonora CavallariDepartment of Molecular Biotechnology and Health Sciences, University of Turin Piazza Nizza 44/bis 10126 Turin Italy enzo.terreno@unito.it.ORCID https://orcid.org/0000-0003-4891-4138
Giuliana MagnaccaDepartment of Chemistry and NIS Interdepartmental Centre, University of Turin Via Pietro Giuria 7 10125 Turin Italy.ORCID https://orcid.org/0000-0002-3798-5232
Mikhail V TrukhanDepartment of Drug Science and Technology, University of Turin Via P. Giuria 9 10125 Turin Italy katia.martina@unito.it.ORCID https://orcid.org/0000-0003-2098-4054
Maria Carmen ValsaniaDepartment of Chemistry and NIS Interdepartmental Centre, University of Turin Via Pietro Giuria 7 10125 Turin Italy.
Giancarlo CravottoDepartment of Drug Science and Technology, University of Turin Via P. Giuria 9 10125 Turin Italy katia.martina@unito.it.ORCID https://orcid.org/0000-0001-7574-7350
Enzo TerrenoDepartment of Molecular Biotechnology and Health Sciences, University of Turin Piazza Nizza 44/bis 10126 Turin Italy enzo.terreno@unito.it.ORCID https://orcid.org/0000-0003-3800-566X
Katia MartinaDepartment of Drug Science and Technology, University of Turin Via P. Giuria 9 10125 Turin Italy katia.martina@unito.it.ORCID https://orcid.org/0000-0003-2256-5021

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work presents a group of high-quality hydrophilic and negatively charged coated, iron oxide magnetic nanoparticles (MNPs) that have been prepared using a microwave-ultrasound-assisted protocol, and demonstrates the great impact that the synthetic strategy has on the resulting MNPs. The different coatings tested, including citric acid, carboxymethyl dextran and β-cyclodextrin (βCD)/citric acid have been compared and have shown good dispersibility and stability. The ability of βCD to maintain the inclusive properties of the coated MNPs has been proven as well as their cytocompatibility. An amino citrate-modified βCD is proposed and its capabilities as a flexible amphoteric adsorbing device have been studied. The NMR relaxometric properties of the coated MNPs have been investigated using field-cycling nuclear magnetic relaxation dispersion profiles. For the amino citrate-modified βCD system, the order of magnitude of the Néel relaxation time is in the typical range for superparamagnetic systems' reversal times,

Identifiers

PMID39569331
PMCPMC11575534

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.