Evidence map›Paper›PMID 39569281›Full record

ArticleCureus2024

Cholesterol Crystal Embolism Following Mechanical Thrombectomy for Acute Ischemic Stroke.

May Pyae Kyaw, Tatsuya Tanaka, Jun Ito, Ryosuke Matsuoka, Mina Komuta, Akira Matsuno

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

May Pyae KyawDepartment of Neurosurgery, International University of Health and Welfare Narita Hospital, Narita, JPN.
Tatsuya TanakaDepartment of Neurosurgery, International University of Health and Welfare Narita Hospital, Narita, JPN.
Jun ItoDepartment of Nephrology, International University of Health and Welfare Narita Hospital, Narita, JPN.
Ryosuke MatsuokaDepartment of Anatomic Pathology, International University of Health and Welfare Narita Hospital, Narita, JPN.
Mina KomutaDepartment of Anatomic Pathology, International University of Health and Welfare Narita Hospital, Narita, JPN.
Akira MatsunoDepartment of Neurosurgery, International University of Health and Welfare Narita Hospital, Narita, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholesterol crystal embolism (CCE) is a rare but serious complication of atherosclerotic plaque rupture, often occurring after endovascular interventions. We report the case of a 73-year-old man who developed CCE following mechanical thrombectomy (MT) for an acute ischemic stroke (AIS) due to left internal carotid artery occlusion. The patient, with a history of hypertension and hyperlipidemia, underwent successful MT with complete recanalization. However, four weeks after the procedure, he presented with blue toe syndrome and acute kidney injury. Histopathological analysis of a skin biopsy confirmed the diagnosis of CCE. The patient's renal function partially improved with corticosteroid therapy. Clinicians should maintain a high level of suspicion for CCE in patients who develop renal dysfunction or peripheral ischemia after MT, particularly in those with significant atherosclerotic risk factors. Early detection and timely intervention are critical for improving outcomes. Further research is warranted to clarify the incidence and optimal management of CCE in the context of MT for AIS.

Indexed as

acute ischemic strokeacute kidney injuryatheroembolic strokeblue toe syndromecholesterol crystal embolismendovascular complicationsmechanical thrombectomyskin biopsy

Identifiers

PMID39569281
PMCPMC11577971

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.