Evidence map›Paper›PMID 39569223›Full record

ArticleCureus2024

The Prevalence of Gastroesophageal Reflux Disease (GERD) in H. pylori-Positive and -Negative Patients.

Walid Alkeridy, Khalid Alanezi, Faisal K Alshehri, Mudafr Alkhedr, Mohammed A Albabtain, Musab Alamri, Rayan Jabaan, Abdulrahman Almugren, Majid Alsahafi, Saad S Alkhowaiter

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In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Walid AlkeridyDepartment of Medicine, College of Medicine, King Saud University, Riyadh, SAU.
Khalid AlaneziDepartment of Medicine, College of Medicine, King Saud University, Riyadh, SAU.
Faisal K AlshehriDepartment of Medicine, College of Medicine, King Saud University, Riyadh, SAU.
Mudafr AlkhedrDepartment of Medicine, College of Medicine, King Saud University, Riyadh, SAU.
Mohammed A AlbabtainDepartment of Medicine, College of Medicine, King Saud University, Riyadh, SAU.
Musab AlamriDepartment of Medicine, College of Medicine, King Saud University, Riyadh, SAU.
Rayan JabaanDepartment of Medicine, College of Medicine, King Saud University, Riyadh, SAU.
Abdulrahman AlmugrenDepartment of Medicine, College of Medicine, King Saud University, Riyadh, SAU.
Majid AlsahafiDivision of Gastroenterology, Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.
Saad S AlkhowaiterDepartment of Medicine - Gastroenterology, College of Medicine, King Saud University, Riyadh, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe presence of Helicobacter pylori (H. pylori) infection can influence gastric acid production. While both gastroesophageal reflux disease (GERD) and H. pylori are highly prevalent in the Saudi Arabian population, the relationship between these two conditions remains uncertain. This study aims to assess the association between GERD and H. pylori.

methodsThis was a cross-sectional study which included patients who underwent endoscopy with gastric biopsy to test for H. pylori. H. pylori status was assessed using histopathology. The GERD-Q questionnaire was used to ascertain the presence of GERD. Multivariate analysis was used to assess the relationship between H. pylori and GERD.

resultsA total of 352 participants were included, with a mean age of 45 years (±14.7) and 58% of them being female. 148 participants (42%) tested positive for H. pylori. 59 (39.9%) had GERD. GERD was identified in 39.9% of the H. pylori-positive group and 37.3% of the H. pylori-negative group. H. pylori was not significantly associated with GERD in the multivariate analysis (P = 0.726, OR = 1.089, 95% CI: 0.675 - 1.759).

conclusionThere was no association between H. pylori infection and GERD in this Saudi Arabian population.

Indexed as

gerdh. pyloriinfectionpatientprevalence

Identifiers

PMID39569223
PMCPMC11578635

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.