Evidence map›Paper›PMID 39569119›Full record

ArticleRSC advances2024

Antileishmanial potential of thiourea-based derivatives: design, synthesis and biological activity.

Abdul Hadi, Muhammad Yaqoob, Fahad Hussain, Yasser M S A Al-Kahraman, Muhammad Saeed Jan, Abid Mahmood, Thomas Shier, Umer Rashid

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdul HadiDepartment of Pharmacy, COMSATS University Islamabad Abbottabad Campus 22060 KPK Pakistan yasser@cuiatd.edu.pk.
Muhammad YaqoobDepartment of Chemistry, COMSATS University Islamabad Abbottabad Campus 22060 KPK Pakistan umerrashid@cuiatd.edu.pk.
Fahad HussainDepartment of Chemistry, COMSATS University Islamabad Abbottabad Campus 22060 KPK Pakistan umerrashid@cuiatd.edu.pk.ORCID https://orcid.org/0009-0000-9304-7948
Yasser M S A Al-KahramanDepartment of Pharmacy, COMSATS University Islamabad Abbottabad Campus 22060 KPK Pakistan yasser@cuiatd.edu.pk.
Muhammad Saeed JanDepartment of Pharmacy, Bacha Khan University 24420 Charsadda KPK Pakistan.ORCID https://orcid.org/0000-0003-2411-6510
Abid MahmoodDepartment of Pharmaceutical Chemistry, Government College University Faisalabad Pakistan.
Thomas ShierDepartment of Medicinal Chemistry, University of Minnesota Minneapolis USA.
Umer RashidDepartment of Chemistry, COMSATS University Islamabad Abbottabad Campus 22060 KPK Pakistan umerrashid@cuiatd.edu.pk.ORCID https://orcid.org/0000-0002-2419-3172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmaniasis is a neglected tropical disease caused by protozoan parasites and transmitted to humans by the sandfly vector. Currently, the disease has limited therapeutic alternatives. Thiourea derivatives were designed, synthesized, and screened for antileishmanial activity. The synthesized compounds 4g, 20a, and 20b demonstrated significant

Identifiers

PMID39569119
PMCPMC11575720

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.