ArticleJournal of obstetrics and gynaecology of India2024
A Non-Inferiority Study on Endometrial Preparation Prior to FET-Letrozole Versus Hormone Replacement Therapy.
Article in Journal of obstetrics and gynaecology of India, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: To compare the efficacy of letrozole-stimulated cycles to the more conventional artificial programmed cycles, in endometrial preparation for frozen embryo transfer (FET), in terms of endometrial parameters, reproductive outcomes, other practical parameters like number of visits to the clinic, cost involved, and patient satisfaction. Methods: This prospective cohort study was conducted at Rao Hospital for a period of 11 months. The study included a total of 152 cycles of frozen embryo transfers. Fifty-five women selected for Group A underwent letrozole FET. Ninety-seven women selected for Group B had an artificial hormone replacement for endometrial preparation, prior to FET. All patients were followed-up with serial ultrasounds and FET done when endometrium reached desired state. Results: The endometrial thickness was comparable in both the groups, and on 3D endostudy, the flow index was non-significantly higher in the hormone replacement therapy (HRT) group. Other variables like vascularity index (VI), volume, and vascularization flow index (VFI) were similar in the two groups. The clinical pregnancy rate was higher in the letrozole group than the artificial cycle group, though not with significant difference. The live birth rate was higher in the patients on HRT than letrozole. The miscarriage rates were comparable in both groups. The medical comorbidities were significantly higher in the HRT cycles. Conclusion: Letrozole FET could be a better alternative to the conventional HRT cycles, in selected population of patients, in terms of reproductive outcomes and patient satisfaction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.