ReviewHeliyon2024
Burden of active tuberculosis among patients with diabetes mellitus in Sub-Saharan Africa: A systematic review and meta-analysis.
Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Addressing key risk factors hindering tuberculosis control activities in West Africa - progress in meeting the UN sustainable development goals.IJID regions · 2025Review
- A Year in Review on Tuberculosis and Non-tuberculous Mycobacteria Disease: A 2025 Update for Clinicians and Scientists.Pathogens & immunity · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The simultaneous occurrence of diabetes mellitus and tuberculosis presents a significant health challenge, complicating diagnosis, treatment, and outcomes. Despite this, tuberculosis screening is not routinely conducted for diabetes patients, and limited information exists regarding tuberculosis prevalence among diabetics in Africa. Thus, this study aimed to determine the pooled prevalence of tuberculosis among diabetes mellitus patients in Sub-Saharan Africa. Methods: A systematic search was conducted in PubMed, Medline, Google Scholar, and African Journal online library databases to identify studies reporting tuberculosis burden among diabetes patients in Sub-Saharan Africa. Data extraction was performed using an Excel spreadsheet, with analysis carried out in Stata version 14. The pooled prevalence was estimated using a Der-Simonian-Laird random-effects model. Heterogeneity among studies was assessed using I-squared test statistics, and subgroup analyses were conducted to identify heterogeneity sources. Risk of bias assessment and sensitivity analysis were also performed. Results: The systematic review and meta-analysis included twelve studies with 13,002 participants. The combined prevalence of tuberculosis among diabetes patients in Sub-Saharan Africa was 4.11 % (95 % confidence interval: 2.97-5.25); I2 = 89.4 %). Subgroup analysis revealed a pooled tuberculosis prevalence of 4.6 % among diabetes patients in East Africa and 2.36 % in Southwestern African countries. Conclusions: This research indicates an elevated prevalence of tuberculosis among diabetes patients in sub-Saharan Africa. The findings highlight the urgent need for tuberculosis screening in diabetes patients and the implementation of effective prevention strategies to address the dual burden of comorbid tuberculosis and diabetes mellitus.
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Registered trials
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