Evidence map›Paper›PMID 39568747›Full record

ArticleFrontiers in medicine2024

Case report: Metagenomic next-generation sequencing for the diagnosis of rare

Xiaocui Liang, Xiaoyu Liu, Zhimin Huang, Fei Qiu, Yini Jiang, Chunhong Li, Zhenfeng Deng, Jinyu Wu

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Case Report: Spinal cord abscess due toFrontiers in medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaocui Liang *Infection Diagnosis Center, Guangxi KingMed Diagnostics, Nanning, China.
Xiaoyu Liu *Department of Rheumatology, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.
Zhimin HuangDepartment of Rheumatology, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.
Fei QiuDepartment of Rheumatology, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.
Yini JiangDepartment of Rheumatology, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.
Chunhong LiInfection Diagnosis Center, Guangxi KingMed Diagnostics, Nanning, China.
Zhenfeng DengInfection Diagnosis Center, Guangxi KingMed Diagnostics, Nanning, China.
Jinyu WuDepartment of Rheumatology, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nocardiosis poses a diagnostic challenge due to its rarity in clinical practice, non-specific clinical symptoms and imaging features, and the limitations of traditional detection methods. Case presentation: A 52-year-old woman with a history of immune thrombocytopenia for over 2 years was hospitalized for recurrent fever and cough lasting for 10 days. Her initial diagnosis on admission was community-acquired pneumonia, based on chest computed tomography findings of lung inflammation lesion. Empirical treatment with moxifloxacin and trimethoprim-sulfamethoxazole (TMP-SMZ) was initiated. However, her condition failed to improve significantly even after 1 week of treatment. Bronchoalveolar lavage fluid (BALF) subjected to mNGS revealed the presence of Conclusion: We report the first detailed case of pulmonary nocardiosis caused by

Indexed as

case reportdiagnosismetagenomic next-generation sequencingNocardia aobensisnocardiosis

Identifiers

PMID39568747
PMCPMC11576201

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.