Evidence map›Paper›PMID 39568719›Full record

ArticleFrontiers in nutrition2024

Influence of altitudes and development stages on the chemical composition and antioxidant capacity of Andean blackberries (

Mabel Guevara-Terán, Eduardo Tejera, Wilson Vásquez-Castillo, Celestino Santos-Buelga, Ana M González-Paramás, José M Alvarez-Suarez

Abstract read
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Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Bioactive Profile, Antioxidant, andAntioxidants (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mabel Guevara-TeránGrupo de Bioquimioinformática, Universidad de Las Américas, Quito, Ecuador.
Eduardo TejeraGrupo de Bioquimioinformática, Universidad de Las Américas, Quito, Ecuador.
Wilson Vásquez-CastilloIngeniería Agroindustrial, Universidad de Las Américas, Quito, Ecuador.
Celestino Santos-BuelgaGrupo de Investigación en Polifenoles, Campus Miguel de Unamuno, Universidad de Salamanca, Salamanca, Spain.
Ana M González-ParamásGrupo de Investigación en Polifenoles, Campus Miguel de Unamuno, Universidad de Salamanca, Salamanca, Spain.
José M Alvarez-SuarezLaboratorio de Investigación en Ingeniería en Alimentos (LabInAli), Departamento de Ingeniería en Alimentos, Colegio de Ciencias e Ingenierías, Universidad San Francisco de Quito USFQ, Quito, Ecuador.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Andean blackberry ( Methods: Andean blackberry fruits were collected at different altitudes and development stages in the central Andean region of Ecuador. An hydroalcoholic extraction was used to quantify the compounds and determine the total antioxidant activity, while solid phase extraction (SPE) was performed to separate anthocyanins from other compounds. Ultra-high-performance liquid chromatography coupled to a triple quadrupole mass spectrometer (HPLC-DAD/ESI-MSn) was used to identify anthocyanin and non-anthocyanin phenols, while total antioxidant capacity, total polyphenols, total flavonoid content, and total anthocyanin content were quantified spectrophotometrically. Results: Flavonols and anthocyanins constitute the majority of the flavonoids identified in the Andean blackberry extracts, both in terms of peak areas and number of identified compounds, followed by ellagic and gallic acid derivatives, as well as phenolic acids, mainly hydroxycinnamic acids. Quercetin was identified as the predominant flavonol in unripe berries, where anthocyanins were not significantly present. On the contrary, in ripe berries, cyanidin and its glycosides stood out as the main anthocyanins and predominant compounds. We observed that in the early stages of ripening, the total polyphenol content predominates in the berries and is mainly responsible for their antioxidant capacity. However, as the fruit ripens, the total anthocyanin content increases, becoming the most prominent bioactive compounds in fully ripe berries. Conclusion: The results suggest that higher altitude environmental conditions may improve the composition, concentration of phenolic compounds, and antioxidant activity of Andean blackberries. Overall, our findings highlight the high functional value of this fruit, supporting its health-protective effects when consumed regularly, either as fresh fruit or in nutraceutical form.

Indexed as

altitudeAndean blackberryAnthocyaninsblackberry chemistryfruit antioxidantsphenolic and flavonoid contentripeness and maturityRosaceae family

Identifiers

PMID39568719
PMCPMC11576316

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.