Evidence map›Paper›PMID 39568555›Full record

ArticleJRSM open2024

Providing personalised care for people with tuberculosis: an evaluation of enhanced case management in a UK TB Network 2013 to 2021.

Tim Crocker-Buque, Harry Hayden, Jacqui White, Jennifer Dekoningh, Moerida Belton, Narinder Boparai, James Brown, Mike Brown, Danielle Hawley, Stefan Lozewicz and 6 more

Abstract read
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In one paragraph

Article in JRSM open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tim Crocker-BuqueDepartment of Infectious Diseases, The Royal Free Hospital NHS Trust, London, UK.ORCID https://orcid.org/0000-0003-0059-7735
Harry HaydenDepartment of Infectious Diseases, The Royal Free Hospital NHS Trust, London, UK.
Jacqui WhiteNorth Central London Tuberculosis Service, The Whittington Hospital NHS Trust, London, UK.
Jennifer DekoninghNorth Central London Tuberculosis Service, The Whittington Hospital NHS Trust, London, UK.
Moerida BeltonNorth Central London Tuberculosis Service, The Whittington Hospital NHS Trust, London, UK.
Narinder BoparaiNorth Central London Tuberculosis Service, The Whittington Hospital NHS Trust, London, UK.
James BrownDepartment of Respiratory Medicine, The Royal Free Hospital NHS Trust, London, UK.
Mike BrownNorth Central London Tuberculosis Service, The Whittington Hospital NHS Trust, London, UK.
Danielle HawleyNorth Central London Tuberculosis Service, The Whittington Hospital NHS Trust, London, UK.
Stefan LozewiczDepartment of Respiratory Medicine, North Middlesex University Hospital, London, UK.
Rob MillerNorth Central London Tuberculosis Service, The Whittington Hospital NHS Trust, London, UK.
Rachel MooresDepartment of Infectious Diseases, The Royal Free Hospital NHS Trust, London, UK.
Karyn MoshalDepartment of Infectious Diseases, Great Ormond Street Hospital for Children NHS Trust, London, UK.
Jessica PotterDepartment of Respiratory Medicine, North Middlesex University Hospital, London, UK.
Marc LipmanDepartment of Respiratory Medicine, The Royal Free Hospital NHS Trust, London, UK.
North Central London Tuberculosis Service

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Evaluating the outcomes of enhanced case management (ECM) for patients with tuberculosis (TB) in the North Central London TB Service (NCLTBS). Design: Retrospective cohort study. Setting: The NCLTBS provides care for persons diagnosed with TB across north and central London. Management involves both medical and psychosocial support, leading to the implementation ECM to provide additional non-clinical assistance to patients at risk of treatment non-completion. However, there has been limited evaluation of its outcomes. Participants: All adults with TB notified to NCLTBS between January 2013 and June 2021. Main outcome measures: Descriptive socio-economic and clinical characteristics grouped by binary ECM status (yes/no) and level (0-3). Clinical outcomes at 12 months (completed treatment, death, lost-to-follow-up, continuing on treatment) were compared using multivariable logistic regression. Results: Totally, 2437 patients were included (57.2% male, 79.1% born outside the UK). Overall, 82.3% completed treatment and 4.1% died. Factors associated with mortality included older age (over 70 years odds ratio (OR) 3.3), inpatient diagnosis (OR 4.4), and mental health issues (OR 2.2). 52.8% received ECM, with the proportion increasing over time, and 76% of this group successfully competed treatment. Conclusions: This comprehensive evaluation of ECM in a diverse London population indicates high treatment completion rates even among those with multiple social risk factors. However, ECM needs of patients has increased over time, with a particular rise in patients requiring the highest support level. Given the small difference between standard care and ECM categories 1 and 2, there may be scope to simplify the system.

Indexed as

effectiveness of careevidence-based practiceinfectious diseasesrespiratory medicinetuberculosis

Identifiers

PMID39568555
PMCPMC11574889

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.