Evidence map›Paper›PMID 39568400›Full record

SynthesisWomen's health (London, England)

Epigenetic changes produced in women victims of intimate partner violence: A systematic review.

Coral González-Martínez, Christian Haarkötter, Elena Carnero-Montoro, Jose A Lorente, Miguel Lorente

Abstract readSystematic Review
In one paragraph

Synthesis in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Coral González-MartínezCentre for Genomics and Oncological Research, Pfizer-University of Granada, PTS Granada, Granada, Spain.ORCID 0000-0002-8055-813X
Christian HaarkötterLABIGEN, Department of Legal Medicine, School of Medicine, PTS, University of Granada, UGR, Granada, Spain.ORCID 0000-0002-4419-4631
Elena Carnero-MontoroCentre for Genomics and Oncological Research, Pfizer-University of Granada, PTS Granada, Granada, Spain.
Jose A LorenteCentre for Genomics and Oncological Research, Pfizer-University of Granada, PTS Granada, Granada, Spain.
Miguel LorenteLABIGEN, Department of Legal Medicine, School of Medicine, PTS, University of Granada, UGR, Granada, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntimate partner violence (IPV) is a prevalent form of violence against women that encompasses physical, sexual, and emotional abuse, as well as controlling behaviors by intimate partners, and predisposes the victims to multiple diseases.

objectiveThis systematic review aims to identify epigenetic marks associated with IPV and the resultant stress experienced by victims.

designThis study is a systematic review conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 guidelines. The review includes a comprehensive search and analysis of relevant literature to identify epigenetic changes associated with IPV. DATA SOURCES AND

methodsA systematic search was conducted across four databases: PubMed, Scopus, Web of Science, and ProQuest, using keywords related to IPV and epigenetics. The inclusion criteria were studies published in scientific journals with an experimental approach, focused on female survivors of gender-based violence, and providing information on epigenetic changes. The review included studies published up to June 15, 2024, with no time limits imposed, focusing on female victims of IPV. The inclusion criteria were studies published in scientific journals with an experimental approach, focused on female survivors of gender-based violence, and providing information on epigenetic changes.

resultsThe results revealed that epigenetic changes associated with IPV predominantly affect genes related to the glucocorticoid receptor, insulin-like growth factors, BDNF, and CPLX genes. These observations suggest that IPV is linked to significant epigenetic modifications in both victims and their offspring.

conclusionIt is concluded that IPV is associated with epigenetic changes both in the woman and in her offspring. These findings underscore the importance of understanding the biological embedding of IPV through epigenetic research to better address the long-term health consequences for women. However, more studies are necessary to validate these results.

Indexed as

Epigenesis, GeneticIntimate Partner ViolenceCrime VictimsFemaleHumanschronic stressepigeneticgender-based violenceintimate partner violencesystematic review

Identifiers

PMID39568400
PMCPMC11580075

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.