ArticleMagnetic resonance in medicine2025
Proton-free induction decay MRSI at 7 T in the human brain using an egg-shaped modified rosette K-space trajectory.
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Proton-free induction decay MRSI at 7 T in the human brain using an egg-shaped modified rosette K-space trajectory.Magnetic resonance in medicine · 2025Article
- Rosette Spectroscopic Imaging for Whole-Brain Slab Metabolite Mapping at 7T: Acceleration Potential and Reproducibility.Human brain mapping · 2025Article
- Exploring in vivo human brain metabolism at 10.5 T: Initial insights from MR spectroscopic imaging.NeuroImage · 2025Article
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Abstract
purposeProton (
methodsAnalytical and synthetic simulations were validated with phantom and in vivo measurements at 7 T. The rosette and modified rosette trajectories were measured in five healthy volunteers in 6 min in a 2D slice in the brain. An elliptical phase-encoding sequence was measured in one volunteer in 22 min, and a 3D sequence was measured in one volunteer within 19 min. The SNR per-unit-time, linewidth, Cramer-Rao lower bounds (CRLBs), lipid contamination, and data quality of the proposed modified rosette trajectory were compared to the rosette trajectory.
resultsUsing the modified rosette trajectories, an improved k-space weighting function was achieved resulting in an SNR per-unit-time increase of up to 12% compared to rosette's and 23% compared to elliptical phase-encoding, dependent on the two additional trajectory parameters. Similar results were achieved for the theoretical SNR calculation based on k-space densities, as well as when using the pseudo-replica method for simulated, in vivo, and phantom data. The CRLBs of γ-aminobutyric acid and N-acetylaspartylglutamate improved non-significantly for the modified rosette trajectory, whereas the linewidths and lipid contamination remained similar.
conclusionBy optimizing the shape of the rosette trajectory, the modified rosette trajectories achieved higher SNR per-unit-time and enhanced data quality at the same scan time.
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