Evidence map›Paper›PMID 39568106›Full record

ArticleInfluenza and other respiratory viruses2024

Influenza in Adults Seeking Care at Seven European Emergency Departments: A Prospective Active Surveillance During the 2019-2020 Influenza Season.

Sélilah Amour, Alberto Perez Rubio, Andrea Orsi, Michael Oppert, Micha Loebermann, Carlos Del Pozo Vegas, Karim Tazarourte, Marion Douplat, Laurent Jacquin, Giancarlo Icardi and 7 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04153331 (Burden of Influenza at Emergency Department Level), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04153331 nacompletednot on this map

Burden of Influenza at Emergency Department Level : BIED

TypeinterventionalSponsorHospices Civils de LyonRan2020 to 2020Enrolled2,487ConditionsEmergencies, FluArmsNasal swab
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Sélilah AmourService d'Hygiène, Epidémiologie, Infectiovigilance et Prévention, Hospices Civils de Lyon, Lyon, France.ORCID 0000-0002-4804-7209
Alberto Perez RubioDirección Médica, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Andrea OrsiDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Michael OppertKlinik für Notfall- und Internistische Intensivmedizin, Klinikum Ernst von Bergmann, Potsdam, Germany.
Micha LoebermannAbteilung für Tropenmedizin und Infektionskrankheiten und Sektion Nephrologie, Universitätsmedizin Rostock, Rostock, Germany.
Carlos Del Pozo VegasDirección Médica, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Karim TazarourteService d'Accueil des Urgences, Hospices Civils de Lyon, Lyon, France.
Marion DouplatService d'Accueil des Urgences, Hospices Civils de Lyon, Lyon, France.
Laurent JacquinService d'Accueil des Urgences, Hospices Civils de Lyon, Lyon, France.
Giancarlo IcardiDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Jonas WalkerKlinik für Notfall- und Internistische Intensivmedizin, Klinikum Ernst von Bergmann, Potsdam, Germany.
Andrea GlassAbteilung für Tropenmedizin und Infektionskrankheiten und Sektion Nephrologie, Universitätsmedizin Rostock, Rostock, Germany.
Joshua NealonSanofi Vaccines, Campus Sanofi Lyon, Lyon, France.
Sandra S ChavesSanofi Vaccines, Campus Sanofi Lyon, Lyon, France.
FERS Study Group
Hélène BricoutSanofi Vaccines, Campus Sanofi Lyon, Lyon, France.ORCID 0000-0002-5439-8064
Philippe VanhemsService d'Hygiène, Epidémiologie, Infectiovigilance et Prévention, Hospices Civils de Lyon, Lyon, France.ORCID 0000-0003-3188-1456

Funding

Sanofi
6 · The paper itself

Abstract

backgroundInfluenza can be associated with nonrespiratory disease presentation, but these are less well documented due to the lack of routine testing for influenza in the healthcare system, especially if patients do not present with influenza-like illness (ILI). We aimed to measure the proportion of influenza cases seeking care at emergency department (ED) for a nontraumatic cause, to describe their clinical presentation and their ED-discharge diagnosis.

methodsThe study was conducted at seven hospitals in France, Spain, Italy and Germany during the 2019-20 influenza season, for a period of 10 weeks. Patients (≥ 18 years) consulting for nontraumatic causes at the ED were invited to participate. Consenting patients provided upper respiratory swab samples for influenza testing by reverse transcription polymerase chain reaction. Clinical and demographic data were collected.

resultsThere were 8678 patients included, 50.7% were female and the median age was 57 years. Among them, 494 (5.7%) were laboratory-confirmed influenza (LCI) cases. Nonetheless, only 24.3% of LCI cases had an ED-discharge of influenza. Of all cases confirmed as influenza, 47.6% had a nonrespiratory discharge diagnosis, which frequency increased with age. ILI case definition from the European Centre for Disease Prevention and Control was the most frequently met among influenza cases (68.6%). Older patients (≥ 65 years) were less frequently identified based on any ILI signs/symptoms.

conclusionOur findings indicate that the impact of influenza among patients seeking care at the ED cannot be easily assessed based on clinical presentation and medical records alone. Preventing influenza among adult population may reduce healthcare utilization.

Indexed as

Emergency Service, HospitalInfluenza, HumanSeasonsAdolescentAdultAgedAged, 80 and overEuropeFemaleHumansMaleMiddle AgedPatient Acceptance of Health CareProspective StudiesYoung Adultemergency department (ED)influenzainfluenza‐like illness (ILI)International Classification of Diseases (ICD) diagnosis

Identifiers

PMID39568106
PMCPMC11578834

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.