Evidence map›Paper›PMID 39568075›Full record

ReviewBiology direct2024

Telomeres: an organized string linking plants and mammals.

Edison Di Pietro, Romina Burla, Mattia La Torre, Mary-Paz González-García, Raffaele Dello Ioio, Isabella Saggio

Abstract readReview
In one paragraph

Review in Biology direct, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edison Di PietroDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza, University of Rome, Rome, Italy.
Romina BurlaDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza, University of Rome, Rome, Italy.
Mattia La TorreDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza, University of Rome, Rome, Italy.
Mary-Paz González-GarcíaCentro de Biotecnología y Genómica de Plantas (Universidad Politécnica de Madrid - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria), UPM-INIA/CSIC. Campus de Montegancedo, Pozuelo de Alarcón, 28223, Madrid, Spain.
Raffaele Dello IoioDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza, University of Rome, Rome, Italy. raffaele.delloioio@uniroma1.it.
Isabella SaggioDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza, University of Rome, Rome, Italy. isabella.saggio@uniroma1.it.

Funding

Fondazione AIRC per la ricerca sul cancro ETS IG-24614Ministero dell'Università e della Ricerca 20229LHY5LPOR FESR Lazio 2014-2020 A0375E0189-2020-36640
6 · The paper itself

Abstract

Telomeres are pivotal determinants of cell stemness, organismal aging, and lifespan. Herein, we examined similarities in telomeres of Arabidopsis thaliana, mice, and humans. We report the common traits, which include their composition in multimers of TTAGGG sequences and their protection by specialized proteins. Moreover, given the link between telomeres, on the one hand, and cell proliferation and stemness on the other, we discuss the counterintuitive convergence between plants and mammals in this regard, focusing on the impact of niches on cell stemness. Finally, we suggest that tackling the study of telomere function and cell stemness by taking into consideration both plants and mammals can aid in the understanding of interconnections and contribute to research focusing on aging and organismal lifespan determinants.

Indexed as

ArabidopsisTelomereAgingAnimalsCell ProliferationHumansMammalsMiceAgingEpigeneticsHumansLifespanMiceNichePlantsShelterinStem cellsTelomeres

Identifiers

PMID39568075
PMCPMC11577926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.