Evidence map›Paper›PMID 39568025›Full record

ArticleDiagnostic pathology2024

Clinical validation on role of cancer diagnostic probe in detecting the involved cavity margins missed in permanent pathology of tumor side in breast cancer surgery.

Fereshteh Abbasvandi, Zohreh Sadat Miripour, Mahdis Bayat, Seyed Mohamad Sadegh Mousavi-Kiasary, Samira Shayanfar, Fatemeh Shojaeian, Faeze Aghaei, Fahimeh Jahanbakhshi, Niloofar Abbasvandi, Maryam Omranihashemi and 9 more

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostic pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Fereshteh Abbasvandi *Nano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Zohreh Sadat Miripour *Nano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Mahdis BayatNano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Seyed Mohamad Sadegh Mousavi-KiasaryNano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Samira ShayanfarCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fatemeh ShojaeianNano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Faeze AghaeiNano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Fahimeh JahanbakhshiNano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Niloofar AbbasvandiNano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Maryam OmranihashemiCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Atieh AkbariCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Morteza YousefiCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad HadizadehNano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Naiemeh Shahrabi FarahaniCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Parisa HosseinpoorNano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran.
Mohammad ParnianiATMP Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, 1517964311, Tehran, Iran.
Zeinab NourinjadATMP Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, 1517964311, Tehran, Iran.
Mohammad AbdolahadNano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, 4563-11155, Tehran, Iran. m.abdolahad@ut.ac.ir.
Mohammad Esmaeil AkbariCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer diagnostic probe (CDP) as a newly entered tool in real-time breast cavity margin evaluation showed great improvement in smart margin shaving intra-operatively. This system increased the rate of involved margin detection to 30% with respect to frozen section. In this study for the first time we showed the independent role of CDP in finding the involved cavity side margins which were not diagnosed by permananet pathology of their tumor side interface. Among 147 detected margins by CDP, 23 lesions with invasive component and ductal carcinoma in-situ/ductal cancerization weren't reported as involved margins in permanent pathology of tumor side. Our gold standard was the histology of cavity margin specimen had been scored as involved lesion by CDP. It seems that even when the permanent pathology of surgical margins is used for final declaration, role of CDP is irreplaceable. This distinguished achievement has been obtained intra-operatively in real-time by CDP while involved report in permanent pathology of tumor margins induce re-surgery for the patient.

Indexed as

Breast NeoplasmsMargins of ExcisionAdultAgedCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingFemaleFrozen SectionsHumansMastectomy, SegmentalMiddle AgedNeoplasm, Residual

Identifiers

PMID39568025
PMCPMC11577628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.