Evidence map›Paper›PMID 39567979›Full record

ArticleBMC medicine2024

Retrospective epidemiologic and genomic surveillance of arboviruses in 2023 in Brazil reveals high co-circulation of chikungunya and dengue viruses.

Augusto César Parreiras de Jesus, Paula Luize Camargos Fonseca, Hugo José Alves, Diego Menezes Bonfim, João Victor Rodrigues Dutra, Filipe Romero Rebello Moreira, Cristiane Pinheiro Toscano de Brito Mendonça, Jéssica Silqueira Hickson Rios, Joice do Prado Silva, Frederico Scott Varella Malta and 15 more

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Article in BMC medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Global Genomic Surveillance.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Article
  3. Article
  4. Article
  5. Integrating metagenomics and metatranscriptomics intoThe Journal of general virology · 2026
    Review
  6. Diagnostic Techniques for Dengue Virus.Current topics in microbiology and immunology · 2026
    Review
  7. Dengue: Historical Aspects.Current topics in microbiology and immunology · 2026
    Article
  8. Review
  9. Revisiting the emergence of the Chikungunya virus in Alagoas, Northeast of Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Augusto César Parreiras de Jesus *Hermes Pardini, Grupo Fleury, Av. das Nações, 2448, Departamento de Pesquisa & Desenvolvimento, Distrito Industrial, Minas Gerais, Vespasiano, 31270-901, Brazil.
Paula Luize Camargos Fonseca *Departamento de Genética, Ecologia E Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270901, Brazil.
Hugo José AlvesDepartamento de Genética, Ecologia E Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270901, Brazil.
Diego Menezes BonfimDepartamento de Genética, Ecologia E Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270901, Brazil.
João Victor Rodrigues DutraDepartamento de Genética, Ecologia E Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270901, Brazil.
Filipe Romero Rebello MoreiraDepartamento de Genética, Instituto de Biologia, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Av. Carlos Chagas Filho 373, Cidade Universitária, Rio de Janeiro, 21941-902, Brazil.
Cristiane Pinheiro Toscano de Brito MendonçaHermes Pardini, Grupo Fleury, Av. das Nações, 2448, Departamento de Pesquisa & Desenvolvimento, Distrito Industrial, Minas Gerais, Vespasiano, 31270-901, Brazil.
Jéssica Silqueira Hickson RiosHermes Pardini, Grupo Fleury, Av. das Nações, 2448, Departamento de Pesquisa & Desenvolvimento, Distrito Industrial, Minas Gerais, Vespasiano, 31270-901, Brazil.
Joice do Prado SilvaHermes Pardini, Grupo Fleury, Av. das Nações, 2448, Departamento de Pesquisa & Desenvolvimento, Distrito Industrial, Minas Gerais, Vespasiano, 31270-901, Brazil.
Frederico Scott Varella MaltaHermes Pardini, Grupo Fleury, Av. das Nações, 2448, Departamento de Pesquisa & Desenvolvimento, Distrito Industrial, Minas Gerais, Vespasiano, 31270-901, Brazil.
Isabela Braga-PazDepartamento de Genética, Ecologia E Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270901, Brazil.
João Locke Ferreira de AraújoDepartamento de Genética, Ecologia E Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270901, Brazil.
Jaqueline Silva de OliveiraSubsecretaria de Vigilância Em Saúde, Secretaria de Estado de Saúde de Minas Gerais, Rodovia Papa João Paulo II 4143, Edifício Minas Gerais, Minas Gerais, Cidade Administrativa, Serra Verde, Belo Horizonte, 31630900, Brazil.
Carolina Senra Alves de SouzaSubsecretaria de Vigilância Em Saúde, Secretaria de Estado de Saúde de Minas Gerais, Rodovia Papa João Paulo II 4143, Edifício Minas Gerais, Minas Gerais, Cidade Administrativa, Serra Verde, Belo Horizonte, 31630900, Brazil.
Sandra Elisa Barbosa da SilvaSubsecretaria de Vigilância Em Saúde, Secretaria de Estado de Saúde de Minas Gerais, Rodovia Papa João Paulo II 4143, Edifício Minas Gerais, Minas Gerais, Cidade Administrativa, Serra Verde, Belo Horizonte, 31630900, Brazil.
Danielle Costa Capistrano ChavesSubsecretaria de Vigilância Em Saúde, Secretaria de Estado de Saúde de Minas Gerais, Rodovia Papa João Paulo II 4143, Edifício Minas Gerais, Minas Gerais, Cidade Administrativa, Serra Verde, Belo Horizonte, 31630900, Brazil.
Renée da Silva CarvalhoSubsecretaria de Vigilância Em Saúde, Secretaria de Estado de Saúde de Minas Gerais, Rodovia Papa João Paulo II 4143, Edifício Minas Gerais, Minas Gerais, Cidade Administrativa, Serra Verde, Belo Horizonte, 31630900, Brazil.
Eneida Santos de OliveiraSecretaria Municipal de Saúde de Belo Horizonte, Minas Gerais, Av. Afonso Pena 2336, Funcionários, Belo Horizonte, 30130-040, Brazil.
Marisa de Oliveira RibeiroInstitute of Technology in Immunobiology Bio-Manguinhos, Oswaldo Cruz Foundation/Fiocruz, Rio de Janeiro, Brazil.
Monica Barcellos ArrudaInstitute of Technology in Immunobiology Bio-Manguinhos, Oswaldo Cruz Foundation/Fiocruz, Rio de Janeiro, Brazil.
Patricia AlvarezInstitute of Technology in Immunobiology Bio-Manguinhos, Oswaldo Cruz Foundation/Fiocruz, Rio de Janeiro, Brazil.
Rennan Garcias MoreiraDepartamento de Genética, Ecologia E Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270901, Brazil.
Renan Pedra de SouzaDepartamento de Genética, Ecologia E Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270901, Brazil.
Danielle Alves Gomes ZauliHermes Pardini, Grupo Fleury, Av. das Nações, 2448, Departamento de Pesquisa & Desenvolvimento, Distrito Industrial, Minas Gerais, Vespasiano, 31270-901, Brazil.
Renato Santana AguiarDepartamento de Genética, Ecologia E Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270901, Brazil. santanarnt@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rapid spread and increase of chikungunya (CHIKV) and dengue (DENV) cases in Brazilian regions in 2023 has raised concerns about the impact of arboviruses on public health. Epidemiological and genomic surveillance was performed to estimate the introduction and spread of CHIKV and DENV in Brazil.

methodsThis study obtained results from the Hermes Pardini (HP), a private medical laboratory, and the Health Department of Minas Gerais state (SES-MG). We investigated the positivity rates of CHIKV and DENV by analyzing the results of 139,457 samples tested for CHIKV (44,029 in 2022 and 95,428 in 2023) and 491,528 samples tested for DENV (163,674 in 2022 and 327,854 in 2023) across the five representative geographical regions of Brazil. Genome sequencing was performed on 80 CHIKV and 153 DENV samples that had been positive for RT-PCR tests.

resultsIn our sampling, the data from CHIKV tests indicated that the Northeast region had the highest regional positivity rate in 2022 (58.1%). However, in 2023, the Southeast region recorded the highest positivity rate (40.5%). With regard to DENV, the South region exhibited the highest regional positivity rate in both 2022 (40.8%) and 2023 (22.7%), followed by the Southeast region in both years (34.8% in 2022; 21.4% in 2023). During the first 30 epidemiological weeks of 2023 in the state of Minas Gerais (MG), there was a 5.8-fold increase in CHIKV cases and a 3.5-fold increase in DENV compared to the same period in 2022. Analysis of 151 new DENV-1 and 80 CHIKV genomes revealed the presence of three main clusters of CHIKV and circulation of several DENV lineages in MG. All CHIKV clades are closely related to genomes from previous Brazilian outbreaks in the Northeast, suggesting importation events from this region to MG. We detected the RNA of both viruses in approximately 12.75% of the confirmed positive cases, suggesting an increase of co-infection with DENV and CHIKV during the period of analysis.

conclusionsThese high rates of re-emergence and co-infection with both arboviruses provide useful data for implementing control measures of Aedes vectors and the urgent implementation of public health politics to reduce the numbers of CHIKV and DENV cases in the country.

Indexed as

Chikungunya FeverChikungunya virusDengueDengue VirusArbovirusesBrazilCoinfectionEpidemiological MonitoringFemaleGenome, ViralHumansMaleRetrospective StudiesArbovirusesChikungunyaCo-infectionDengueGenomic and epidemiological surveillance

Identifiers

PMID39567979
PMCPMC11577721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.