Evidence map›Paper›PMID 39567904›Full record

ArticleBMC cardiovascular disorders2024

Tailored bi-atrial linear ablation guided by electrophysiological mapping for persistent atrial fibrillation.

Yuanjun Sun, Shiyu Dai, Xianjie Xiao, Zhongzhen Wang, Xiaohong Yu, Chengming Ma, Rongfeng Zhang, Lianjun Gao, Yunlong Xia, Xiaomeng Yin

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06952023 (Pulsed Field-Based Bi-atrial Maze-like Catheter Ablation Versus Pulmonary Vein Isolation in Persistent Atrial Fibrillation), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06952023 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Pulsed Field-Based Bi-atrial Maze-like Catheter Ablation Versus Pulmonary Vein Isolation in Persistent Atrial Fibrillation: A Multi-center Randomized Controlled Trial

TypeinterventionalSponsorThe First Affiliated Hospital of Dalian Medical UniversityRan2025 to 2027Enrolled390ConditionsAtrial Fibrillation, Persistent Atrial FibrillationArmsModified Maze ablation with PFA, PVI only with PFA
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuanjun Sun *Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China.
Shiyu Dai *Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China.
Xianjie XiaoDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China.
Zhongzhen WangDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China.
Xiaohong YuDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China.
Chengming MaDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China.
Rongfeng ZhangDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China.
Lianjun GaoDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China.
Yunlong XiaDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China. yunlong_xia@126.com.
Xiaomeng YinDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Rd, Dalian, Liaoning, 116011, China. dr.yinxm@163.com.

Funding

Medical master program YXMJ-LJ-12
6 · The paper itself

Abstract

aimTo explore the safety and efficacy of a novel strategy (bi-atrial linear catheter ablation guided by electrophysiological mapping) for persistent atrial fibrillation (PeAF) treatment.

methods83 patients with PeAF were enrolled for evaluation of ablation strategy. 43 patients were subjected to pulmonary vein isolation (PVI) strategy (PVI group). 40 patients were subjected to bi-atrial linear ablation strategy guided by electrophysiological mapping (PVI, left atrial BOX ablation, coronary sinus endocardial linear ablation, tailored left atrial anterior wall linear ablation, mitral isthmus linear ablation with necessary ethanol infusion into the vein of Marshall, right atrial posterior wall linear ablation and cavo-tricuspid isthmus ablation) (linear ablation group). Patients were followed up every 3 months.

resultsDuring a median follow-up of 12 (4-16) months, freedom from atrial fibrillation/atrial tachycardia recurrence was 87.5% in the linear ablation group and 65.1% in the PVI group (P < 0.01). A Cox regression multivariate analysis revealed that ablation strategy group (tailored bi-atrial linear ablation) (HR 0.33, 95% CI 0.12-0.91, P = 0.03) was the only independent predictor of recurrence.

conclusionTailored bi-atrial linear ablation strategy guided by electrophysiological mapping resulted in improved outcomes without compromising safety for patients with PeAF.

Indexed as

Action PotentialsAtrial FibrillationCatheter AblationElectrophysiologic Techniques, CardiacHeart RatePulmonary VeinsRecurrenceAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsProgression-Free SurvivalRetrospective StudiesRisk FactorsCatheter ablationElectrophysiological mapping guidanceLinear ablationPersistent atrial fibrillation

Identifiers

PMID39567904
PMCPMC11577918

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Registered trials

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