ArticleNature2024
A spatial human thymus cell atlas mapped to a continuous tissue axis.
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Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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66citing papers in PubMed
–field-weighted citation impact
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Who cites it
66 citing papers in PubMed.
- Article
- Thymic APC Networks Orchestrate T-Cell Selection: Mechanisms and Therapeutic Opportunities in Immune Disorders.Immunology · 2026Review
- Weighted sliced inverse regression for scalable supervised dimensionality reduction of spatial transcriptomics data.Nature communications · 2026Article
- Article
- Association between prenatal exposure to acid-suppressive medications and subsequent risk of autoimmune diseases in offspring: a nationwide birth cohort study in South Korea.World journal of pediatrics : WJP · 2026Article
- CellRank: consistent and data view agnostic fate mapping for single-cell genomics.Nature protocols · 2026Review
- Trimodal, uncertainty-guided whole-slide framework for genome-scale spatial expression and image-only virtual perturbation in cancer cohorts.Genome medicine · 2026Article
- LYNX: a deep generative model for linking spatial dynamics and cell interactions in multimodal spatial data.bioRxiv : the preprint server for biology · 2026Article
- Thymic output in human newborns is shaped by environmental exposures and a common TCRD genetic variant.Journal of human immunity · 2026Article
- Fibroblast-driven collagen expansion and altered thymic medullary niches in 22q11.2 deletion syndrome.Journal of human immunity · 2026Article
- scDifformer: diffusion-based post-training for virtual cell modeling across large-scale single-cell data.Nucleic acids research · 2026Article
- A dependency-aware deep generative model for inferring RNA velocity from spatial transcriptomics.Bioinformatics (Oxford, England) · 2026Article
- ZFP36L1 and ZFP36L2 cooperatively regulate thymic epithelial cell function to prevent early-onset thymic involution.Cell death and differentiation · 2026Article
- Spatiotemporal cell type deconvolution leveraging tissue structure.Research square · 2026Article
- Structural and mechanistic insights into the constitutive Themis-Grb2 complex in T cell signalling.Nature communications · 2026Article
- A single-cell atlas revealing cellular heterogeneity across healthy and diseased human thymus.Nature communications · 2026Article
- Article
- Topological velocity inference from spatial transcriptomic data.Nature biotechnology · 2026Article
- Mapping cell fate transition in space and time.Nature biotechnology · 2026Article
- CCR4 expression defines a targetable subset of T-cell acute lymphoblastic leukemia.Blood advances · 2026Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
- Update of
Authors and funding
45 authors.
Nadav Yayon *Cellular Genetics, Wellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-7034-0524
Veronika R Kedlian *Cellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Lena Boehme *Department of Diagnostic Sciences, Ghent University, Ghent, Belgium.ORCID 0000-0001-7593-7533
Chenqu SuoCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Brianna T WachterLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD, USA.ORCID 0000-0002-2950-2683
Rebecca T BeuschelLaboratory of Immune System Biology, Lymphocyte Biology Section and Center for Advanced Tissue Imaging, National Institute of Allergy and Infectious Diseases (NIH), Bethesda, MD, USA.
Oren AmsalemDivision of Endocrinology, Diabetes and Metabolism, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID 0000-0002-8070-0378
Krzysztof PolanskiCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Simon KoplevCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Elizabeth TuckCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Emma DannCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Jolien Van HulleDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Shani PereraCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Tom PuttemanDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Alexander V PredeusCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-2750-1599
Monika DabrowskaCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Laura RichardsonCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Catherine TudorCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.ORCID 0000-0003-2093-9683
Alexandra Y KreinsDepartment of Immunology and Gene Therapy, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Justin EngelbertFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Emily StephensonCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Vitalii KleshchevnikovCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Fabrizio De RitaDepartment of Adult Congenital Heart Disease and Paediatric Cardiology/Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
David CrosslandDepartment of Adult Congenital Heart Disease and Paediatric Cardiology/Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
Marita BosticardoLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD, USA.
Francesca PalaLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD, USA.ORCID 0000-0003-4537-9061
Elena PrigmoreCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.ORCID 0000-0001-8870-0316
Nana-Jane ChipampeCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-8802-0473
Martin PreteCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-5946-821X
Lijiang FeiCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Ken ToCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Roger A BarkerDepartment of Clinical Neurosciences, John van Geest Centre for Brain Repair, University of Cambridge, Cambridge, UK.ORCID 0000-0001-8843-7730
Xiaoling HeDepartment of Clinical Neurosciences, John van Geest Centre for Brain Repair, University of Cambridge, Cambridge, UK.ORCID 0009-0004-1002-8418
Filip Van NieuwerburghLaboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium.ORCID 0000-0001-8815-5485
Omer Ali BayraktarCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Minal PatelCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
E Graham DaviesDepartment of Immunology and Gene Therapy, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Muzlifah A HaniffaCellular Genetics, Wellcome Sanger Institute, Cambridge, UK.
Virginie UhlmannEuropean Bioinformatics Institute, European Molecular Biology Laboratory, Cambridge, UK.ORCID 0000-0002-2859-9241
Luigi D NotarangeloLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD, USA.ORCID 0000-0002-8335-0262
Ronald N GermainLaboratory of Immune System Biology, Lymphocyte Biology Section and Center for Advanced Tissue Imaging, National Institute of Allergy and Infectious Diseases (NIH), Bethesda, MD, USA. rgermain@niaid.nih.gov.ORCID 0000-0003-1495-9143
Andrea J RadtkeLaboratory of Immune System Biology, Lymphocyte Biology Section and Center for Advanced Tissue Imaging, National Institute of Allergy and Infectious Diseases (NIH), Bethesda, MD, USA. andrea.radtke@nih.gov.ORCID 0000-0003-4379-8967
John C MarioniEuropean Bioinformatics Institute, European Molecular Biology Laboratory, Cambridge, UK. marioni@ebi.ac.uk.ORCID 0000-0001-9092-0852
Tom TaghonDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium. tom.taghon@ugent.be.ORCID 0000-0002-5781-0288
Sarah A TeichmannCellular Genetics, Wellcome Sanger Institute, Cambridge, UK. sat1003@cam.ac.uk.ORCID 0000-0002-6294-6366
Funding
Medical Research Council MC_PC_17230Medical Research Council MR/W000830/1Wellcome Trust
Abstract
T cells develop from circulating precursor cells, which enter the thymus and migrate through specialized subcompartments that support their maturation and selection
Indexed as
Epithelial CellsSingle-Cell AnalysisThymocytesThymus GlandAtlases as TopicCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell LineageCytokinesData AnalysisData CurationFetal DevelopmentHumansInfant, NewbornMaleOrgan SpecificityCytokines
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.