ArticleNature2024
Single-cell integration reveals metaplasia in inflammatory gut diseases.
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In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.
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0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Understanding heterogeneity in the pathogenesis and drug responses of ulcerative colitis through single-cell and spatial transcriptomics.Frontiers in immunology · 2026Pooled it
- Research trends of intestinal barrier in ulcerative colitis: a bibliometric analysis.Frontiers in medicine · 2025Pooled it
- Using In Silico Pseudobulk Differential Expression and Trajectory Analysis of Single Cell RNA Sequencing to Reveal Stem Cell State Transitions in Colonic Inflammation.Methods in molecular biology (Clifton, N.J.) · 2027Article
- Molecular histomorphometry and the emerging role of transcriptomics in celiac disease diagnosis and therapeutic trials.Annals of medicine · 2026Review
- Diverse infections transcriptionally reprogram the intestinal epithelium and epithelial-immune cell interactions.Nature immunology · 2026Article
- A human single-cell atlas identifies OLR1Nature genetics · 2026Article
- Phenotypic switching of gastrointestinal smooth muscle cells and the regulatory role of macrophages: a literature review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Review
- IL1B-high macrophages promote ferroptosis-like lipid peroxidation injury in Crohn's disease intestinal epithelium.Redox biology · 2026Article
- Vascular and lymphatic dysregulation via non-EndoMT Col2a1 signaling in bisphosphonate-related osteonecrosis of the jaw.Nature communications · 2026Article
- Article
- Epigenetic modulation of stromal cell states underpins pathological tissue niches in Crohn's disease.Nature immunology · 2026Article
- Mapping mesenchymal diversity in the human small intestine and organoids.Nature cell biology · 2026Article
- Current Status of Intestinal Stem Cell Research: Mechanisms, Intestinal Diseases, and Organoid Development.Cells · 2026Review
- scGenoByte: a GenoByte embedding transformer with biological priors for cell type annotation.Briefings in bioinformatics · 2026Article
- Long QT syndrome and hypoglycemia in a postbariatric surgery patient with a likely pathogenic variant inJCEM case reports · 2026Article
- Single-cell RNA sequencing of terminal ileal biopsies identifies signatures of Crohn's disease pathogenesis.Nature genetics · 2026Article
- Single-nucleus interrogation of primate small intestinal aging reveals NCoR1 decline as a conserved feature that is reversed by metformin.Nature aging · 2026Article
- Basal gland localization and focal distribution of OLFM4-expressing cells in increasing severity of gastric intestinal metaplasia.bioRxiv : the preprint server for biology · 2026Article
- Colonic epithelial regeneration shapes susceptibility tobioRxiv : the preprint server for biology · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
54 authors.
Amanda J OliverWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0003-1690-9027
Ni HuangWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0001-8849-038X
Raquel Bartolome-CasadoWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-8966-9047
Ruoyan LiWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0001-5337-9729
Simon KoplevWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Hogne R NilsenDepartment of Pathology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, Norway.
Madelyn MoyWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Batuhan CakirWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0003-4513-606X
Krzysztof PolanskiWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-2586-9576
Victoria GudiñoInflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.
Elisa Melón-ArdanazInflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.
Dinithi SumanaweeraWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Daniel DimitrovInstitute for Computational Biomedicine, Heidelberg University, Faculty of Medicine, Heidelberg University Hospital, Bioquant, Heidelberg, Germany.
Lisa Marie MilchsackWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0009-0003-4284-5263
Michael E B FitzPatrickTranslational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0003-2365-2012
Nicholas M ProvineTranslational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-9694-2216
Jacqueline M BoccacinoWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0001-6813-5217
Emma DannWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-7400-7438
Alexander V PredeusWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-2750-1599
Ken ToWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Martin PreteWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-5946-821X
Jonathan A ChapmanTranslational and Clinical Research Institute, Newcastle University, Newcastle, UK.
Andrea C MasiTranslational and Clinical Research Institute, Newcastle University, Newcastle, UK.
Emily StephensonWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Justin EngelbertWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Sebastian LobentanzerInstitute for Computational Biomedicine, Heidelberg University, Faculty of Medicine, Heidelberg University Hospital, Bioquant, Heidelberg, Germany.
Shani PereraWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Laura RichardsonWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-8075-3816
Rakeshlal KapugeWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0009-0001-3394-0387
Anna Wilbrey-ClarkWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Claudia I SemprichWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-2446-9028
Sophie EllamsWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Catherine TudorWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0003-2093-9683
Philomeena JosephWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Alba Garrido-TrigoInflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.
Ana M CorralizaInflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.ORCID 0000-0002-3067-7763
Thomas R W OliverDepartment of Histopathology and Cytology, Cambridge University Hospitals, Cambridge, UK.ORCID 0000-0003-4306-0102
C Elizabeth HookDepartment of Pathology, University of Cambridge, Cambridge, UK.
Kylie R JamesTranslational Genomics, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID 0000-0002-7107-0650
Krishnaa T MahbubaniDepartment of Surgery, University of Cambridge, Cambridge, UK.ORCID 0000-0002-1327-2334
Kourosh Saeb-ParsyDepartment of Surgery, University of Cambridge, Cambridge, UK.ORCID 0000-0002-0633-3696
Matthias ZilbauerCambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
Julio Saez-RodriguezInstitute for Computational Biomedicine, Heidelberg University, Faculty of Medicine, Heidelberg University Hospital, Bioquant, Heidelberg, Germany.ORCID 0000-0002-8552-8976
Marte Lie HøivikDepartment of Gastroenterology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-0104-465X
Espen S BækkevoldDepartment of Pathology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, Norway.
Christopher J StewartTranslational and Clinical Research Institute, Newcastle University, Newcastle, UK.ORCID 0000-0002-6033-338X
Janet E BerringtonTranslational and Clinical Research Institute, Newcastle University, Newcastle, UK.
Kerstin B MeyerWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0001-5906-1498
Paul KlenermanTranslational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Azucena SalasInflammatory Bowel Disease Unit, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.ORCID 0000-0003-4572-2907
Muzlifah HaniffaWellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-3927-2084
Frode L JahnsenDepartment of Pathology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, Norway.
Rasa Elmentaite *Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Sarah A Teichmann *Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. sat1003@cam.ac.uk.ORCID 0000-0002-6294-6366
Funding
Medical Research Council MC_PC_17230Medical Research Council MR/W000830/1Wellcome Trust
Abstract
The gastrointestinal tract is a multi-organ system crucial for efficient nutrient uptake and barrier immunity. Advances in genomics and a surge in gastrointestinal diseases
Indexed as
Epithelial CellsGastrointestinal DiseasesInflammationMetaplasiaSingle-Cell AnalysisAdultBrunner GlandsCase-Control StudiesCeliac DiseaseChildColitis, UlcerativeCrohn DiseaseDatasets as TopicGastric MucosaGastrointestinal NeoplasmsGastrointestinal Tract
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.