Evidence map›Paper›PMID 39567710›Full record

ArticleJournal of exposure science & environmental epidemiology2025

Air pollution mixture exposure during pregnancy and postpartum psychological functioning: racial/ethnic- and fetal sex-specific associations.

Yueh-Hsiu Mathilda Chiu, Brent A Coull, Ander Wilson, Hsiao-Hsien Leon Hsu, Naim Xhani, Farida Nentin, Barbara C Deli, Joel Schwartz, Elena Colicino, Robert O Wright and 1 more

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yueh-Hsiu Mathilda ChiuDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA. mathilda.chiu@mssm.edu.ORCID http://orcid.org/0000-0003-1656-660X
Brent A CoullDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Ander WilsonDepartment of Statistics, Colorado State University, Fort Collins, CO, USA.
Hsiao-Hsien Leon HsuDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Naim XhaniDepartment of Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Farida NentinDepartment of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Barbara C DeliDepartment of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Elena ColicinoDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Robert O WrightDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rosalind J WrightDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Chris Gennings · 2014 to 2026
$21.3M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUG3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CARROLL, KECIA NICOLE, WRIGHT, ROBERT O · 2016 to 2024
$20.6M
Stress, Environment, and Genetics in Urban AsthmaR01HL080674 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2005 to 2014
$7.0M
Perinatal Programming of Infant Stress Reactivity and the Atopic PhenotypeR01HL095606 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOSQUET ENLOW, MICHELLE A, WRIGHT, ROSALIND J · 2010 to 2013
$3.1M
MULTI-LEVEL ANALYSIS OF URBAN CHILDHOOD ASTHMA RISKR01ES010932 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2000 to 2004
$3.0M
Air pollution, stress and urban child developmentR01MD006086 · NIMHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2010 to 2014
$2.2M
Asthma Coalition on Community, Environment and StressU01HL072494 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2002 to 2003
$1.5M
NCATS NIH HHS UL1 TR004419NHLBI NIH HHS R01 HL080674NHLBI NIH HHS R01 HL095606NHLBI NIH HHS U01 HL072494NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R01 ES010932NIH HHS UG3 OD023337NIMHD NIH HHS R01 MD006086
6 · The paper itself

Abstract

backgroundPrenatal air pollution (AP) exposure has been linked to postpartum psychological functioning, impacting health outcomes in both women and children. Extant studies primarily focused on individual pollutants.

objectiveTo assess the association between prenatal exposure to a mixture of seven AP components and postpartum psychological functioning using daily exposure data and data-driven statistical methods.

methodsAnalyses included 981 women recruited at 24.0 ± 9.9 weeks gestation and followed longitudinally. We estimated prenatal daily exposure levels for constituents of fine particles [elemental carbon (EC), organic carbon (OC), nitrate (NO

resultsWomen were primarily Hispanic (51%) and Black (32%) reporting ≤12 years of education (58%). Prenatal exposure to an AP mixture was significantly associated with increased anhedonia subscale z-scores, particularly in Hispanics (β = 0.07, 95%CI = 0.004-0.13, per unit increase in WQS index). It was also borderline associated with increased total EPDS (β = 0.11, 95%CI = 0.00-0.22) and depressive symptom subscale (β = 0.09, 95%CI = -0.02 to 0.19) z-scores, particularly among Hispanic women who gave birth to a male infant. Sulfate (SO IMPACT: This study utilizes an advanced data-driven approach to examine the temporally- and mixture-weighted effects of prenatal air pollution exposure on postpartum psychological functioning. We found that exposure to a prenatal air pollution mixture predicted poorer postpartum psychological functioning, particularly anhedonia symptoms in Hispanic women. Findings underscore the importance of considering both exposure mixtures as well as potential modifying factors to better help identify particular pollutants that drive effects and susceptible populations, which can inform more effective intervention strategies.

Indexed as

Air PollutantsAir PollutionDepression, PostpartumMaternal ExposurePostpartum PeriodPrenatal Exposure Delayed EffectsAdultEthnicityFemaleHumansLongitudinal StudiesMaleOzoneParticulate MatterPregnancySex FactorsAir PollutantsOzoneParticulate MatterAir pollutionHealth disparitiesMixturePostpartum depressionPrenatal exposure

Identifiers

PMID39567710
PMCPMC12092737

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.