ArticleNature2024
Broadly inhibitory antibodies to severe malaria virulence proteins.
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In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16citing papers in PubMed
–field-weighted citation impact
What it found
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Who cites it
16 citing papers in PubMed.
- Equitable access to monoclonal antibodies targeting parasites.Trends in parasitology · 2026Review
- ETS-guided iPSC-endothelial models recapitulate malaria pathogenesis.EMBO molecular medicine · 2026Article
- Predictive value of PfEMP1 antibody profiles for the course of controlled human malaria infections.PLoS pathogens · 2026Article
- CAR-macrophage therapy: a novel strategy to overcome antimalarial drug resistance by targeting PfEMP1-mediated adhesion.Malaria journal · 2026Article
- Longitudinal plasma metabolomics reveals a role for taurine in asymptomatic malaria and seasonal persistence.Nature microbiology · 2026Article
- Article
- Technological advancements in antibody-based therapeutics for treatment of diseases.Journal of biomedical science · 2025Review
- Comparative genomics, integrated with single-cell sequencing and genetic analyses, reveal roles of transcription factor AP2-M2 in asexual replication of Babesia parasite.PLoS pathogens · 2025Article
- Febrile temperature enhancesbioRxiv : the preprint server for biology · 2025Article
- Identification of broadly inhibitory anti-PfEMP1 antibodies by mass spectrometry sequencing of plasma IgG from a malaria-exposed child.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Plasmodium falciparum infection induces T cell tolerance that is associated with decreased disease severity upon re-infection.The Journal of experimental medicine · 2025Article
- Leveraging microphysiological systems to expedite understanding of host-parasite interactions.PLoS pathogens · 2025Review
- Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration.Communications biology · 2025Article
- Malaria monoclonals block brain binding.Trends in parasitology · 2025Article
- Breaking the bind: PfEMP1-specific antibodies in cerebral malaria.Frontiers in immunology · 2025Review
- Detection of naturally acquired, strain-transcending antibodies against rosettingInfection and immunity · 2024Article
Corrections and comments
- Update of
Authors and funding
29 authors.
Raphael A Reyes *Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.ORCID 0000-0002-2234-4758
Sai Sundar Rajan Raghavan *Centre for Translational Medicine and Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.ORCID 0000-0002-2575-2685
Nicholas K Hurlburt *Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID 0000-0001-9891-916X
Viola Introini *EMBL Barcelona, Barcelona, Spain.ORCID 0000-0001-9012-4696
Sebastiaan BolDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.ORCID 0000-0002-3843-6657
Ikhlaq Hussain KanaCentre for Translational Medicine and Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.
Rasmus W JensenCentre for Translational Medicine and Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.
Elizabeth Martinez-ScholzeDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
María Gestal-MatoEMBL Barcelona, Barcelona, Spain.ORCID 0000-0002-5096-2609
Borja López-GutiérrezEMBL Barcelona, Barcelona, Spain.ORCID 0000-0002-7159-5836
Silvia SanzEMBL Barcelona, Barcelona, Spain.ORCID 0000-0003-4334-3284
Cristina BancellsEMBL Barcelona, Barcelona, Spain.
Monica Lisa Fernández-QuinteroDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID 0000-0002-6811-6283
Johannes R LoefflerDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
James Alexander FergusonDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
Wen-Hsin LeeDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID 0000-0001-9445-6671
Greg Michael MartinDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
Thor G TheanderCentre for Translational Medicine and Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.
John P A LusinguNational Institute for Medical Research, Tanga Research Centre, Tanga, Tanzania.
Daniel T R MinjaNational Institute for Medical Research, Tanga Research Centre, Tanga, Tanzania.
Isaac SsewanyanaInfectious Disease Research Collaboration, Kampala, Uganda.
Margaret E FeeneyDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-2515-2989
Bryan GreenhouseDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Andrew B WardDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID 0000-0001-7153-3769
Maria BernabeuEMBL Barcelona, Barcelona, Spain.ORCID 0000-0001-7212-6209
Marie PanceraVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID 0000-0001-9217-6270
Louise TurnerCentre for Translational Medicine and Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark. lturner@sund.ku.dk.ORCID 0000-0003-4494-2289
Evelien M BunnikDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. bunnik@uthscsa.edu.ORCID 0000-0003-4003-3053
Thomas LavstsenCentre for Translational Medicine and Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark. thomasl@sund.ku.dk.ORCID 0000-0002-3044-4249
Funding
TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1MTransmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joaniter Immaculate Nankabirwa · 2010 to 2026
$29.3MThe role of γδ T cells in fetal and infant immune defense against malariaR01AI093615 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FEENEY, MARGARET E · 2011 to 2025
$9.1MComputational models of naturally acquired immunity to falciparum malariaU01AI150741 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUTTE, ATUL J, GREENHOUSE, BRYAN R · 2020 to 2024
$7.4MDefining conserved epitopes on polymorphic malaria antigensR01AI153425 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BUNNIK, EVELIEN MARGARETHA · 2021 to 2025
$2.7MNRSA Training Core (TL1)TL1TR002647 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHUN, YONG-HEE PATRICIA, FREI, CHRISTOPHER R. · 2018 to 2022
$1.8MAcquisition of a Rigaku XtaLAB Synergy-R macromolecular diffraction instrumentation at Fred Hutchinson Cancer Research CenterS10OD028581 · OD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI STODDARD, BARRY L. · 2020 to 2020
$600kFACSAria Fusion cell sorter for Flow Cytometry Shared ResourceS10OD030432 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BERTON, MICHAEL T · 2022 to 2022
$596kMolecular and cellular properties of broad and protective immune responses to the Plasmodium falciparum variant surface antigen responsible for severe malariaF31AI169993 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI REYES, RAPHAEL ANTHONY · 2022 to 2023
$46kEuropean Molecular Biology LaboratoryNCATS NIH HHS TL1 TR002647NCI NIH HHS P30 CA054174NIAID NIH HHS F31 AI169993NIAID NIH HHS R01 AI093615NIAID NIH HHS R01 AI153425NIAID NIH HHS U01 AI150741NIAID NIH HHS U19 AI089674NIH HHS S10 OD028581NIH HHS S10 OD030432Wellcome Trust
Abstract
Malaria pathology is driven by the accumulation of Plasmodium falciparum-infected erythrocytes in microvessels
Indexed as
Antibodies, ProtozoanBroadly Neutralizing AntibodiesMalaria, FalciparumPlasmodium falciparumProtozoan ProteinsVirulenceVirulence FactorsAnimalsAntibodies, MonoclonalBinding SitesBrainEndothelial Protein C ReceptorErythrocytesHumansMalaria VaccinesMicrovesselsAntibodies, MonoclonalAntibodies, ProtozoanBroadly Neutralizing AntibodiesEndothelial Protein C Receptorerythrocyte membrane protein 1, Plasmodium falciparumMalaria VaccinesPROCR protein, humanProtozoan ProteinsVirulence Factors
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.