Evidence map›Paper›PMID 39567655›Full record

ArticleEuropean journal of clinical nutrition2025

Associations between perinatal biomarkers of maternal dairy fat intake and child cognitive development: results from the EDEN mother-child cohort.

Wen Lun Yuan, Martine Armand, Hugo Peyre, Catherine Sarté, Marie Aline Charles, Barbara Heude, Jonathan Y Bernard

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Article in European journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wen Lun YuanUniversité Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Center for Research in Epidemiology and StatisticS (CRESS), Paris, France. wenlun.yuan@inserm.fr.ORCID http://orcid.org/0000-0002-7472-5042
Martine ArmandAix Marseille Univ, CNRS, CRMBM, Marseille, France.ORCID http://orcid.org/0000-0002-8712-6620
Hugo PeyreCentre de Ressources Autisme Languedoc-Roussillon et Centre d'Excellence sur l'Autisme et les Troubles Neuro-développementaux, CHU Montpellier, Montpellier cedex 05, France.
Catherine SartéAix Marseille Univ, CNRS, CRMBM, Marseille, France.
Marie Aline CharlesUniversité Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Center for Research in Epidemiology and StatisticS (CRESS), Paris, France.
Barbara Heude *Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Center for Research in Epidemiology and StatisticS (CRESS), Paris, France.ORCID http://orcid.org/0000-0002-1565-1629
Jonathan Y Bernard *Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Center for Research in Epidemiology and StatisticS (CRESS), Paris, France.ORCID http://orcid.org/0000-0002-6418-983X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveOffspring's optimal neurodevelopment depends on maternal dietary lipids supply during the perinatal period. Dairy products are an important source of fat in Western diets. This study aimed at examining the associations between maternal dairy fat intake during pregnancy, evaluated through biomarkers in perinatal biofluids (C15:0 and C17:0) and child's cognitive outcomes. SUBJECTS/

methodsParticipants (N up to 1200) were French mother-child pairs from the EDEN cohort study. Biomarkers were assessed in the following biofluids: maternal red blood cells (RBC) membrane at 24 weeks' gestation, cord RBC membrane, and colostrum. Cognitive outcomes were language abilities scores at ages 2 and 3 years and overall cognitive development scores at ages 3 and 5-6 years. Associations were assessed using multiple linear regression models adjusted for factors related to family socioeconomic context, maternal lifestyle, and healthy diet score. Interaction of any breastfeeding duration on the associations with dairy fat biomarkers in colostrum was studied.

resultsPositive associations were observed between levels of C17:0 in cord RBC and C15:0 in maternal RBC with language abilities. In children breastfed for at least 6 months, C15:0 level in colostrum was positively associated with language abilities at age 3 years and overall cognitive development at ages 3 and 5-6 years whereas C17:0 level was only associated with overall cognitive development at age 3 years.

conclusionOur results suggest that maternal higher intake of dairy fat during perinatal period could be potentially associated with offspring's better cognitive development. These pioneering results call for external validation to challenge their causality.

Indexed as

Child DevelopmentCognitionDairy ProductsDietary FatsMaternal Nutritional Physiological PhenomenaAdultBiomarkersBreast FeedingChildChild, PreschoolCohort StudiesColostrumFemaleFetal BloodHumansMaleBiomarkersDietary Fats

Identifiers

PMID39567655

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