Evidence map›Paper›PMID 39567373›Full record

ArticleEuropean journal of nutrition2024

Pre- and post-polyphenol intake and ovarian cancer survival: evidence from a prospective cohort study.

Jia-Nan Sun, Yu Li, Meng Luan, Lang Wu, Fang-Hua Liu, Yi-Zi Li, He-Li Xu, Yi-Fan Wei, Qian Xiao, Xiao-Ying Li and 5 more

Abstract read
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In one paragraph

Article in European journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jia-Nan Sun *Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Yu Li *Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Meng Luan *Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Lang WuCancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI, USA.
Fang-Hua LiuDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Yi-Zi LiDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
He-Li XuDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Yi-Fan WeiDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Qian XiaoDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Xiao-Ying LiDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Jin XuDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Ke-Xin LiuDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Dong-Hui HuangDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China. huangdh@sj-hospital.org.
Qi-Jun WuDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China. wuqj@sj-hospital.org.ORCID http://orcid.org/0000-0001-9421-5114
Ting-Ting GongDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China. gongtt@sj-hospital.org.

Funding

National Natural Science Foundation of China 82073647National Natural Science Foundation of China 82103914National Natural Science Foundation of China 82373674
6 · The paper itself

Abstract

purposeAlthough (poly)phenols have shown potential in anti-cancer activities, their impact on improving ovarian cancer (OC) survival remains unknown. Therefore, we aim to first investigate the association between dietary polyphenol intake and OC survival, providing valuable insights into potential interventions.

methodsThe prospective cohort recruited 560 patients with OC to assess the associations of polyphenol intake, not only pre- and post-diagnosis but also the change from pre- to post-diagnosis with OC survival. Dietary intakes of total (poly)phenols and their five classes (flavonoids, phenolic acids, lignans, stilbenes, and other polyphenols) were assessed using a validated 111-item food frequency questionnaire. Overall survival (OS) was tracked through active follow-up and medical records until February 16th, 2023. Cox proportional hazard regression models were applied to calculate the hazard ratios (HR) and 95% confidence intervals (CI).

resultsDuring a median follow-up of 44.4 months, 211 all-cause deaths were identified. We observed significant associations between higher polyphenol intake with lower risk of mortality among patients with OC ((HR

conclusionDietary (poly)phenols, as well as its five classes, have an inverse association with OC survival.

Indexed as

DietOvarian NeoplasmsPolyphenolsAdultAgedCohort StudiesFemaleFollow-Up StudiesHumansMiddle AgedProportional Hazards ModelsProspective StudiesSurvival AnalysisPolyphenolsCohortDietFlavonoidOvarian cancerPolyphenolSurvival

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