Evidence map›Paper›PMID 39567250›Full record

SynthesisInnovations (Philadelphia, Pa.)

Totally Endoscopic Coronary Artery Bypass Graft: Systematic Review and Meta-Analysis of Reconstructed Patient-Level Data.

Ioannis Zoupas, Vasiliki Manaki, Panagiotis T Tasoudis, Nina-Rafailia Karela, Dimitrios V Avgerinos, Konstantinos S Mylonas

Registry-linked trialAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Innovations (Philadelphia, Pa.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07755072 (The Effect of Ligament of Marshall Excision During Minimally Invasive Cardiac Surgery-Coronary Artery Bypass Grafting), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07755072 nanot yet recruitingnot on this map

The Effect of Ligament of Marshall Excision During Minimally Invasive Cardiac Surgery-Coronary Artery Bypass Grafting (MICS-CABG) on the Prevention of Postoperative New-Onset Atrial Fibrillation: A Multicenter, Prospective, Randomized, Triple-Blinded Study

TypeinterventionalSponsorPeking University Third HospitalRan2026 to 2028Enrolled628ConditionsPostoperative Atrial FibrillationArmsMICS-CABG combined with excision of the Ligament of Marshall
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ioannis ZoupasCardiothoracic and Vascular Surgery Working Group, Society of Junior Doctors, Athens, Greece.ORCID 0000-0003-4077-7407
Vasiliki ManakiCardiothoracic and Vascular Surgery Working Group, Society of Junior Doctors, Athens, Greece.
Panagiotis T TasoudisCardiothoracic and Vascular Surgery Working Group, Society of Junior Doctors, Athens, Greece.
Nina-Rafailia KarelaCardiothoracic and Vascular Surgery Working Group, Society of Junior Doctors, Athens, Greece.
Dimitrios V AvgerinosDepartment of Cardiac Surgery, Onassis Cardiac Surgery Center, Athens, Greece.
Konstantinos S MylonasDepartment of Cardiac Surgery, Onassis Cardiac Surgery Center, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe standard approach for coronary artery bypass grafting is open surgery. Totally endoscopic coronary artery bypass has emerged as an alternative for selected patients. This meta-analysis sought to evaluate clinical outcomes with this emerging technique.

methodsA PRISMA-compliant search was performed up to December 14, 2022, in PubMed (MEDLINE), Scopus, and Cochrane. Time-to-event data were reconstructed using Kaplan-Meier curves from source literature.

resultsA total of 2,774 patients with symptomatic coronary artery disease underwent totally endoscopic coronary artery bypass in 18 eligible studies. The mean patient age was 63.2 ± 12.3 years, and 77.5% (95% confidence interval [CI]: 72.2% to 82.4%) of the included patients were males. The mean operative time was 304.2 ± 155 min, whereas the mean internal mammary artery takedown time was 38.3 ± 18.4 min. Of the patients, 4.7% (95% CI: 1.6% to 9.1%) required conversions to open surgery. The 30-day complication rate was 5.9% (95% CI: 1.2% to 13.1%), whereas late complications developed in 4.8% (95% CI: 1.9% to 8.5%) of the patients. Freedom from major adverse cardiac events was 93.4% (95% CI: 85.3% to 94.8%) and 1-year, 5-year, and 10-year survival rates were 95.2%, 83.2%, and 81.7%, respectively. Reintervention was required in 3.3% (95% CI: 2.3% to 4.4%) of the cohort within a mean follow-up of 42.5 ± 27.8 months.

conclusionsTotally endoscopic coronary artery bypass may be a safe and viable alternative for selected patients with coronary artery disease. Long-term follow-up will help define the place of robotic endoscopic treatment in the armamentarium of myocardial revascularization.

Indexed as

Coronary Artery BypassCoronary Artery DiseaseEndoscopyAgedFemaleHumansMaleMiddle AgedOperative TimePostoperative ComplicationsTreatment OutcomeCABGcardiac surgerycoronary artery bypass graftendoscopicminimally invasiverobotic

Identifiers

PMID39567250
PMCPMC11656624

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.