Evidence map›Paper›PMID 39567015›Full record

ArticleThe Journal of veterinary medical science2025

A pilot study investigating serum carnitine profile of cats with preclinical hypertrophic cardiomyopathy.

Mutsuki Umezawa, Takuma Aoki, Seiya Niimi, Hiroshi Takano, Kazuya Mamada, Yoko Fujii

Abstract read
In one paragraph

Article in The Journal of veterinary medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mutsuki UmezawaLaboratory of Small Animal Surgery, Azabu University, Kanagawa, Japan.
Takuma AokiLaboratory of Small Animal Surgery, Azabu University, Kanagawa, Japan.
Seiya NiimiLaboratory of Small Animal Surgery, Azabu University, Kanagawa, Japan.
Hiroshi TakanoVeterinary Specialists Emergency Center, Saitama, Japan.
Kazuya MamadaVeterinary Specialists Emergency Center, Saitama, Japan.
Yoko FujiiLaboratory of Small Animal Surgery, Azabu University, Kanagawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to prospectively investigate the hypothesis that myocardial energy metabolism changes in the early stages of feline hypertrophic cardiomyopathy (HCM) by evaluating the blood carnitine profiles. Fourteen client owned cats with HCM stage B1 and 22 clinically healthy cats were included in this study. Total-carnitine, free-carnitine, acylcarnitine, and acylcarnitine/free-carnitine ratio (AF ratio) in serum were measured in both groups. No significant differences were observed in total-carnitine, free-carnitine, and acylcarnitine concentrations between the groups. However, the AF ratio in the HCM group was significantly lower than that of the control group (P=0.02). The lower serum AF ratio in cats with early-stage HCM, may suggest an alteration in their myocardial energy metabolism.

Indexed as

Cardiomyopathy, HypertrophicCarnitineCat DiseasesAnimalsCase-Control StudiesCatsFemaleMalePilot ProjectsProspective StudiesacylcarnitineCarnitineacquired heart diseasecardiac energeticsfeline cardiologypathophysiology

Identifiers

PMID39567015
PMCPMC11735214

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.