Evidence map›Paper›PMID 39566992›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Positive Antiganglioside Antibodies in a Patient with Primary Diffuse Large B-cell Lymphoma of the Central Nervous System.

Ryoji Nishi, Haruki Koike, Tomoya Maekawa, Yoshitaka Nakamura, Yohei Kawade, Takashi Tsujiuchi, Masasuke Ohno, Yuki Fukami, Masahisa Katsuno, Takafumi Sagisaka

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ryoji NishiDepartment of Neurology, Daido Hospital, Japan.
Haruki KoikeDivision of Neurology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
Tomoya MaekawaDepartment of Neurology, Daido Hospital, Japan.
Yoshitaka NakamuraDepartment of Neurology, Daido Hospital, Japan.
Yohei KawadeDepartment of Neurology, Daido Hospital, Japan.
Takashi TsujiuchiDepartment of Neurosurgery, Daido Hospital, Japan.
Masasuke OhnoDepartment of Neurosurgery, Aichi Cancer Center Hospital, Japan.
Yuki FukamiDepartment of Neurology, Nagoya University Graduate School of Medicine, Japan.
Masahisa KatsunoDepartment of Neurology, Nagoya University Graduate School of Medicine, Japan.
Takafumi SagisakaDepartment of Neurology, Daido Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Up to one-third of lymphoma cases involve the nervous system. Miller-Fisher syndrome (MFS) associated with lymphoma is extremely rare. We herein report a case of primary central nervous system lymphoma initially mimicking MFS in a 70-year-old man who presented with subacute unsteady gait and diplopia. A neurological examination revealed unilateral ophthalmoplegia, ataxia, and areflexia. The patient tested positive for anti-GQ1b antibodies, so MFS was initially suspected. However, the progression extended over one month. Subsequently, disturbance of consciousness was observed. Cranial magnetic resonance imaging revealed lesions in the periventricular fourth ventricle, and a brain biopsy indicated diffuse large B-cell lymphoma.

Indexed as

AutoantibodiesCentral Nervous System NeoplasmsGangliosidesLymphoma, Large B-Cell, DiffuseAgedDiagnosis, DifferentialHumansMagnetic Resonance ImagingMaleMiller Fisher SyndromeAutoantibodiesGangliosidesGQ1b gangliosideanti-GQ1b antibodyanti-GQ1b syndromeBickerstaff brainstem encephalitisdiffuse large B-cell lymphomaMiller-Fisher syndromeprimary central nervous system lymphoma

Identifiers

PMID39566992
PMCPMC12241723

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.