Evidence map›Paper›PMID 39566977›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Successful Allogeneic Hematopoietic Stem Cell Transplantation for Nodal Epstein-Barr Virus-positive T/NK-cell Lymphoma.

Satoshi Ichikawa, Hiroaki Abe, Naoya Morota, Akihisa Kawajiri, Ryo Nakagawa, Kyoko Inokura, Shunsuke Hatta, Yuna Katsuoka, Koichi Onodera, Noriko Fukuhara and 4 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Satoshi IchikawaDepartment of Hematology, Tohoku University Hospital, Japan.
Hiroaki AbeDepartment of Hematology, Tohoku University Hospital, Japan.
Naoya MorotaDepartment of Hematology, Tohoku University Hospital, Japan.
Akihisa KawajiriDepartment of Hematology, Tohoku University Hospital, Japan.
Ryo NakagawaDepartment of Hematology, Tohoku University Hospital, Japan.
Kyoko InokuraDepartment of Hematology, Tohoku University Hospital, Japan.
Shunsuke HattaDepartment of Hematology, Tohoku University Hospital, Japan.
Yuna KatsuokaDepartment of Hematology, Sendai Medical Center, Japan.
Koichi OnoderaDepartment of Hematology, Tohoku University Hospital, Japan.
Noriko FukuharaDepartment of Hematology, Tohoku University Hospital, Japan.
Yasushi OnishiDepartment of Hematology, Tohoku University Hospital, Japan.
Hisayuki YokoyamaDepartment of Hematology, Tohoku University Hospital, Japan.
Ryo IchinohasamaDepartment of Hematopathology, Tohoku University Hospital, Japan.
Hideo HarigaeDepartment of Hematology, Tohoku University Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nodal Epstein-Barr virus-positive T/NK-cell lymphoma (EB-nTNKL) is an extremely rare disease characterized by an aggressive clinical course and poor prognosis, for which treatment strategies have not yet been established. We herein report a young man with EB-nTNKL. Although initial chemotherapies, including L-asparaginase, failed to produce a good response, subsequent myeloablative allogeneic hematopoietic stem cell transplantation (alloHSCT) resulted in favorable disease control and a long-term disease-free survival. The prompt performance of alloHSCT using an available donor source at that time, regardless of whether or not the initial chemotherapy was effective, could be critical to saving patients with this otherwise fatal disease.

Indexed as

Epstein-Barr Virus InfectionsHematopoietic Stem Cell TransplantationHerpesvirus 4, HumanLymphoma, Extranodal NK-T-CellAdultHumansMaleTransplantation, HomologousTreatment Outcomeallogeneic hematopoietic stem cell transplantationEpstein-Barr virus-positive T/NK-cell tumorsL-asparaginasenodal Epstein-Barr virus-positive T/NK-cell lymphoma

Identifiers

PMID39566977
PMCPMC12241791

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.