Evidence map›Paper›PMID 39565957›Full record

ArticleBlood advances2025

Therapies and outcomes following extramedullary relapse of pediatric and young adult ALL after CD19 CAR T-cell therapy.

Barbara D Friedes, Amanda M DiNofia, Emma Iannone, Yimei Li, Susan R Rheingold, Allison Barz Leahy, Lisa Wray, Colleen Callahan, Diane Baniewicz, Lauren Vernau and 5 more

Abstract read
In one paragraph

Article in Blood advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Barbara D FriedesDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA.
Amanda M DiNofiaDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.
Emma IannoneDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.
Yimei LiDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.ORCID 0000-0001-9067-6992
Susan R RheingoldDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.ORCID 0000-0001-8025-6767
Allison Barz LeahyDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.ORCID 0000-0002-1368-4064
Lisa WrayDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.
Colleen CallahanDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.
Diane BaniewiczDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.
Lauren VernauDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.
Kelly D GetzDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-2020-5153
Richard AplencDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.
Shannon L MaudeDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.
Stephan A GruppDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.ORCID 0000-0001-8030-7595
Regina M MyersDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.ORCID 0000-0002-2542-2061

Funding

Defining and overcoming intrinsic T cell dysfunction to enable pediatric immunotherapyU01CA232361 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI GRUPP, STEPHAN A., WEBER, EVAN WILLIAM · 2019 to 2019
$3.7M
Optimizing outcomes for children and young adults with relapse of B-cell acute lymphoblastic leukemia after CD19-targeted chimeric antigen receptor T-cell therapyK08CA277013 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI Regina M Myers · 2023 to 2026
$721k
NCI NIH HHS K08 CA277013NCI NIH HHS U01 CA232361
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39565957
PMCPMC11787456

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.