Evidence map›Paper›PMID 39565919›Full record

ArticlePain medicine (Malden, Mass.)2025

Proinflammatory diet is associated with higher pain, disease severity and biochemical parameters associated with inflammation in fibromyalgia.

Nursena Ersoy Söke, Hansa İnceöz, İlker Solmaz, Hülya Yardımcı

Abstract readMulticenter Study
In one paragraph

Article in Pain medicine (Malden, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nursena Ersoy SökeInstitute of Health Sciences, Ankara University, Ankara 06110, Türkiye.ORCID 0000-0003-4327-0775
Hansa İnceözAnkara Etlik City Hospital, Neurology-Orthopedic Hospital, Ankara 06170, Türkiye.
İlker SolmazTraditional and Complementary Medicine Practice Center, University of Health Sciences, Ankara 06010, Türkiye.
Hülya YardımcıFaculty of Health Sciences, Ankara University, Ankara 06290, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFibromyalgia, which is becoming increasingly common today, affects the quality of life of those affected. The aim of this study was to investigate the relationship between diet and pain, disease severity, and biochemical parameters in fibromyalgia.

designCross-sectional design using validated questionnaires.

settingFibroyalgia patients with Traditional and Complementary Medicine clinics. SUBJECT: In total, 84 patients with fibromyalgia (FM), which was diagnosed by a rheumatologist.

methodsThe cross-sectional study was conducted with 84 fibromyalgia patients in Turkey. The Dietary Inflammatory Index (DII) was calculated by a 24-hour diet recall. Self-reported pain levels and disease severity were evaluated by the Visual Analog Scale (VAS) and a Revised Fibromyalgia Impact Questionnaire (FIQR), respectively. Antropometric measures and biochemical parameters associated with inflammation were also evaluated.

resultsLinear regression analysis revealed that the VAS pain score [β (95% confidence interval [CI])=1.72 (0.90-2.55), P < .001], FIQ-R [β (95% CI)=5.62 (0.14-11.09), P < .001] and uric acid/creatinine ratio [β (95% CI)=0.21 (-0.10 to 0.52), P < .001] were positively associated with the DII after adjustments for body mass index (BMI), body fat, fat free mass, cholesterol, fiber, caroten, iron, magnesium, vitamine C reported by the patients with FM.

conclusionsA pro-inflammatory diet was associated with higher pain, disease severity and uric acid/creatinine ratio in patients with FM.

Indexed as

DietFeeding BehaviorFibromyalgiaInflammationPainAdultCreatinineCross-Sectional StudiesDiet SurveysFemaleHumansLinear ModelsMaleMiddle AgedPain MeasurementSeverity of Illness IndexCreatinineUric Aciddietary ınflammatory ındexfibromyalgialife quality: nutrientspain

Identifiers

PMID39565919
PMCPMC11879218

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.