Evidence map›Paper›PMID 39565719›Full record

ArticleAnnals of the New York Academy of Sciences2025

Protective effects of exercise on responses to combined social and environmental stress in prairie voles.

Dmitry S Kovalev, Alex Amidei, Oreoluwa I Akinbo-Jacobs, Jessica Linley, Teva Crandall, Linnea Endsley, Angela J Grippo

Abstract read
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In one paragraph

Article in Annals of the New York Academy of Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dmitry S KovalevDepartment of Psychology, Northern Illinois University, DeKalb, Illinois, USA.
Alex AmideiDepartment of Psychology, Northern Illinois University, DeKalb, Illinois, USA.
Oreoluwa I Akinbo-JacobsDepartment of Psychology, Northern Illinois University, DeKalb, Illinois, USA.
Jessica LinleyDepartment of Psychology, Northern Illinois University, DeKalb, Illinois, USA.
Teva CrandallDepartment of Psychology, Northern Illinois University, DeKalb, Illinois, USA.
Linnea EndsleyDepartment of Psychology, Northern Illinois University, DeKalb, Illinois, USA.
Angela J GrippoDepartment of Psychology, Northern Illinois University, DeKalb, Illinois, USA.

Funding

Sex-specific mechanisms of exercise underlying resilience to social stressR15HL147179 · NHLBI · NORTHERN ILLINOIS UNIVERSITY · PI GRIPPO, ANGELA J · 2020 to 2020
$373k
NHLBI NIH HHS R15 HL147179NIH HHS HL147179
6 · The paper itself

Abstract

The combination of social and environmental stressors significantly influences psychological and physical health in males and females, and contributes to both depression and cardiovascular diseases. Animal models support these findings. Voluntary exercise may protect against some forms of stress; however, the protective effects of exercise against social stressors require further investigation. This study evaluated the influence of exercise on the impact of combined social and environmental stressors in socially monogamous prairie voles. Following a period of social isolation plus additional chronic environmental stress, prairie voles were either allowed access to a running wheel in a larger cage for 2 weeks or remained in sedentary conditions. A behavioral stress task was conducted prior to and following exercise or sedentary conditions. Heart rate (HR) and HR variability were evaluated after exercise or sedentary conditions. Group-based analyses indicated that exercise prevented elevated resting HR and promoted autonomic control of the heart. Exercise was also effective against social and environmental stress-induced forced swim test immobility. Some minor sex differences in behavior were observed in response to exercise intensity. This research informs our understanding of the protective influence of physical exercise against social and environmental stressors in male and female humans.

Indexed as

ArvicolinaePhysical Conditioning, AnimalStress, PsychologicalAnimalsBehavior, AnimalFemaleHeart RateMaleSocial Isolationcardiacdepressionexerciseprairie volesocial isolationstress

Identifiers

PMID39565719
PMCPMC11779585

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.