Evidence map›Paper›PMID 39565526›Full record

ArticleUpdates in surgery2025

Differences in the epidemiology and survival of patients with colorectal cancer between China and the United States: a large cross-sectional study.

Yu Shen, Hongyu Cai, Dan Zhou, Jinliang Gao, Tinghan Yang, Haining Chen, Mingtian Wei, Ziqiang Wang

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Updates in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu Shen *Department of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, Sichuan Province, No. 37 Guo Xue Xiang Street, Chengdu, China.
Hongyu Cai *School of Economics, Sichuan University, Sichuan Province, Chengdu, China.
Dan Zhou *Department of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, Sichuan Province, No. 37 Guo Xue Xiang Street, Chengdu, China.
Jinliang GaoCollege of Computer Science, Sichuan University, Sichuan Province, Chengdu, China.
Tinghan YangDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, Sichuan Province, No. 37 Guo Xue Xiang Street, Chengdu, China.
Haining ChenDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, Sichuan Province, No. 37 Guo Xue Xiang Street, Chengdu, China. hnchen@scu.edu.cn.
Mingtian WeiDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, Sichuan Province, No. 37 Guo Xue Xiang Street, Chengdu, China. mtweiyy15@scu.edu.cn.
Ziqiang WangDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, Sichuan Province, No. 37 Guo Xue Xiang Street, Chengdu, China.

Funding

National Natural Science Foundation of China 82103541National Natural Science Foundation of China 82203394National Natural Science Foundation of China 82203474Science and Technology Department of Sichuan Province 2021YFS0025Science and Technology Department of Sichuan Province 2022YFS0209Science and Technology Department of Sichuan Province 2023NSFSC1834Science and Technology Department of Sichuan Province No. 2022YFS0162West China Hospital, Sichuan University 2019HXFH031West China Hospital, Sichuan University 20HXJS003West China Hospital, Sichuan University 22HXFH001West China Hospital, Sichuan University ZYJC21017
6 · The paper itself

Abstract

Studying the epidemiological and management characteristics of colorectal cancer (CRC) between China and the US has important implications. The present cross-sectional study included patients from SEER and Southwest China Colorectal (SCC) databases. Incidence, treatment and survival information were compared between two countries. 86859 patients in the SEER database and 5838 patients in the SCC database were included. The estimated incidence of CRC in the US was greater than that in China from 2006 to 2019. The most common tumor sites of CRC patients in China were the RSC (66.5%), RCC (20.2%) and LCC (13.3%), while those in the US were the RCC (44.4%), RSC (29.8%) and LCC (25.8%). Chinese CRC patients were more likely to be male (58.9% vs 52.4%, p < 0.001), have a greater stage II CRC rate (49.8% vs 27.8%, p < 0.001), younger age at diagnosis (median 64 vs 66 years, p < 0.001). Radical surgery rates were lower in Chinese RCC (92.3% vs 93.9%, p < 0.001) and LCC (88.9% vs 92.0%, p < 0.001) patients. The adjuvant therapy rates were lower in Chinese CRC patients. The 5-year overall survival rates were 71.8% and 78.2% for Chinese and US CRC patients, respectively (p < 0.001). China is undergoing an increasing incidence of CRC. The treatment and mortality of CRC differ in China and US populations. China had a lower adjuvant therapy rate and a lower 5-year OS rate compared with the US.

Indexed as

Colorectal NeoplasmsAdultAgedAged, 80 and overChinaCross-Sectional StudiesFemaleHumansIncidenceMaleMiddle AgedNeoplasm StagingSEER ProgramSurvival RateUnited StatesColorectal cancerEpidemiologyIncidenceSurvival

Identifiers

PMID39565526

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