Evidence map›Paper›PMID 39565505›Full record

Trial reportCurrent medical science2024

Wearable EEG Neurofeedback Based-on Machine Learning Algorithms for Children with Autism: A Randomized, Placebo-controlled Study.

Xian-Na Wang, Tong Zhang, Bi-Cheng Han, Wei-Wei Luo, Wen-Hui Liu, Zhao-Yi Yang, A Disi, Yue Sun, Jin-Chen Yang

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Current medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Brain-computer interface: an update for the clinicians.Frontiers in human neuroscience · 2026
    Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xian-Na WangCapital Medical University School of Rehabilitation Medicine, Beijing, 100068, China.
Tong ZhangCapital Medical University School of Rehabilitation Medicine, Beijing, 100068, China. Tom611@126.com.
Bi-Cheng HanQiangnao Keji (BrainCo) Ltd., Hangzhou, 310027, China.
Wei-Wei LuoCapital Medical University School of Rehabilitation Medicine, Beijing, 100068, China.
Wen-Hui LiuCapital Medical University School of Rehabilitation Medicine, Beijing, 100068, China.
Zhao-Yi YangQiangnao Keji (BrainCo) Ltd., Hangzhou, 310027, China.
A DisiBrainCo., Inc., Somerville, Massachusetts, 02143, USA.
Yue SunBrainCo., Inc., Somerville, Massachusetts, 02143, USA.
Jin-Chen YangQiangnao Keji (BrainCo) Ltd., Hangzhou, 310027, China. jinchen.yang@brainco.tech.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBehavioral interventions have been shown to ameliorate the electroencephalogram (EEG) dynamics underlying the behavioral symptoms of autism spectrum disorder (ASD), while studies have also demonstrated that mirror neuron mu rhythm-based EEG neurofeedback training improves the behavioral functioning of individuals with ASD. This study aimed to test the effects of a wearable mu rhythm neurofeedback training system based on machine learning algorithms for children with autism.

methodsA randomized, placebo-controlled study was carried out on 60 participants aged 3 to 6 years who were diagnosed with autism, at two center-based intervention sites. The neurofeedback group received active mu rhythm neurofeedback training, while the control group received a sham neurofeedback training. Other behavioral intervention programs were similar between the two groups.

resultsAfter 60 sessions of treatment, both groups showed significant improvements in several domains including language, social and problem behavior. The neurofeedback group showed significantly greater improvements in expressive language (P=0.013) and cognitive awareness (including joint attention, P=0.003) than did the placebo-controlled group.

conclusionArtificial intelligence-powered wearable EEG neurofeedback, as a type of brain-computer interface application, is a promising assistive technology that can provide targeted intervention for the core brain mechanisms underlying ASD symptoms.

Indexed as

ElectroencephalographyMachine LearningNeurofeedbackWearable Electronic DevicesAlgorithmsAutism Spectrum DisorderAutistic DisorderChildChild, PreschoolFemaleHumansMaleartificial intelligenceautism spectrum disorderbrain-computer interfacemu rhythmneurofeedback trainingwearable technology

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.