Evidence map›Paper›PMID 39565424›Full record

ArticleMetabolic brain disease2024

Understanding Aβ

Harkomal Verma, Sharanjot Kaur, Priyanka Jeeth, Puneet Kumar, Saraboji Kadhirvel, Monisha Dhiman, Anil Kumar Mantha

Abstract read
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In one paragraph

Article in Metabolic brain disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Harkomal VermaDepartment of Zoology, School of Basic Sciences, Central University of Punjab, VPO - Ghudda, Bathinda, 151 401, Punjab, India.ORCID 0009-0002-0744-2357
Sharanjot KaurDepartment of Microbiology, School of Basic Sciences, Central University of Punjab, Ghudda, Bathinda, Punjab, India.ORCID 0009-0009-7225-525X
Priyanka JeethDepartment of Computational Sciences, School of Basic Sciences, Central University of Punjab, Ghudda, Bathinda, Punjab, India.ORCID 0009-0009-3876-8270
Puneet KumarDepartment of Pharmacology, Central University of Punjab, Ghudda, Bathinda, Punjab, India.ORCID 0000-0002-7978-1043
Saraboji KadhirvelDepartment of Computational Sciences, School of Basic Sciences, Central University of Punjab, Ghudda, Bathinda, Punjab, India.ORCID 0000-0002-4876-4443
Monisha DhimanDepartment of Microbiology, School of Basic Sciences, Central University of Punjab, Ghudda, Bathinda, Punjab, India.ORCID 0000-0001-5923-3384
Anil Kumar ManthaDepartment of Zoology, School of Basic Sciences, Central University of Punjab, VPO - Ghudda, Bathinda, 151 401, Punjab, India. anil.mantha@cup.edu.in.ORCID 0000-0001-6310-725X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The central nervous system (CNS) involves a complex interplay of communications between the neurons and various glial cells, which is crucial for brain functions. The major interactomes are exosomes that transmit sundry molecules (DNA, miRNAs, and proteins) between the cells and thus alter cell physiology. Exosomes can act as neuroprotective or neurodegenerative agents depending on the microenvironment of cells secreting them. Therefore, revealing exosome proteome becomes important to understand donor cells' physiology and its effect on the recipient cell. In this study, oxidative stress was induced by Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesExosomesNeuroblastomaOxidative StressPeptide FragmentsProteomeCell Line, TumorCoumaric AcidsHumansNeuronsNeuroprotective AgentsProteomicsAmyloid beta-Peptidesamyloid beta-protein (25-35)Coumaric Acidsferulic acidNeuroprotective AgentsPeptide FragmentsProteomeAlzheimer’s diseaseAmyloid betaExosomal proteomeExosomesFerulic acidNETosisNeurodegenerationNeuroprotection

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.